Therapeutic Target-Humanized Mice
Cre/Dre-Driver Mice
Immunodeficient NMG Mice
Strain Name:C57BL/6Smoc-Dppa3em1(IRES-Cre)Smoc Strain State:Repository Live | Cat. NO.:NM-KI-00040 Validation Data:Presence | Publications:1piece
The IRES-Cre cassette was inserted into 3'UTR of Dppa(Stella) gene which express during embryonic development.
Strain Name:C57BL/6Smoc-Cd55tm(hCD55)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-215008 Validation Data:Presence
The endogenous mouse Cd55 gene was replaced by human CD55 gene.
Strain Name:C57BL/6Smoc-Cd44tm(hCD44)Smoc Strain State:Repository Live | Cat. NO.:NM-HU-215003 Validation Data:Presence
The endogenous mice Cd44 gene was replaced by human CD44 gene.
Strain Name:C57BL/6Smoc-Slc17a7em1(IRES2-iCre)Smoc Strain State:Repository Live | Cat. NO.:NM-KI-200086 Validation Data:Presence
A IRES2-iCre expression cassette was knocked into the Slc17a7 gene stop codon site.
Strain Name:C57BL/6Smoc-Mrc1em2(2A-CreERT2)Smoc Strain State:Repository Live | Cat. NO.:NM-KI-220031 Validation Data:Presence
2A-CreERT2 expression cassette was knocked into the Mrc1 gene stop codon site.
Strain Name:C57BL/6Smoc-Il12betm3(hIL12B)/Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000057 Validation Data:Presence
The endogenous mouse Il12b gene was replaced by human IL12B gene.
Strain Name:C57BL/6Smoc-Trp63em1(DreERT2-Wpre-polyA)Smoc Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190029 Validation Data:Presence | Publications:1piece
A DreERT2-Wpre-polyA expression cassette was knocked into the exon4 of Trp63 gene.
Strain Name:C57BL/6Smoc-Il2ratm1(hIL2RA)Il2rgtm1(IL2RG)Il2rbtm1(hIL2RB)Smoc Strain State:Repository Live | Cat. NO.:NM-HU-210414 Validation Data:Presence
hIL2RA(NM-HU-190064) was crossed with hIL2RG/hILRB(NM-HU-210354) to generate hIL2RA/hIL2RB/hIL2RG mice.
Strain Name:C57BL/6Smoc-Pdcd1lg2tm1(hPDCD1LG2)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)/Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190060
The endogenous mouse Pd-1/Pd-l1/Pdcd1lg2 gene was replaced by human PD-1/PD-L1/PDCD1LG2 gene.
Strain Name:C57BL/6Smoc-Tg(hCEACAM5)1Smoc Strain State:Sperm cryopreservation | Cat. NO.:NM-TG-225005 Validation Data:Presence
These transgenic mice harbor hCEACAM5 expression cassettes.
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