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Models

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Mice

hIL4/hIL4R

Strain Name：C57BL/6Smoc-Il4tm3(hIL4)Il4ratm1(hIL4R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000106
Validation Data：Presence

These mice are obtained through breeding of two single gene humanized mice.

Mice

hCYP2D6

Strain Name：C57BL/6Smoc-Cyp2dtm(hCYP2D6)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215024

The endogenous mouse Cyp2d22 gene was replaced by human CYP2D6 gene.

Mice

hTIGIT(3)

Strain Name：C57BL/6Smoc-Tigittm3(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200244
Validation Data：Presence

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(Stock No.NM-HU-00053) mice function similarly to hTIGIT（3） mice ,for more detailed information please contact our technical advisor.

Mice

Cd200-KO

Strain Name：C57BL/6Smoc-Cd200em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190029

This Cd200 knockout mouse model was generated by knocking out the exon 2 region of the Cd200 .

Mice

hIL11RA

Strain Name：C57BL/6Smoc-Il11ra1tm1(hIL11RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204982

The endogenous mice Il11ra1 gene was replaced by human IL11RA gene.

Mice

hTNFRSF10B

Strain Name：C57BL/6Smoc-Tnfrsf10btm1(hTNFRSF10B)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210005

The endogenous mice Tnfrsf10B gene was replaced by human TNFRSF10B gene

Mice

Emx1-IRES-Cre

Strain Name：C57BL/6Smoc-emx1em1(IRES-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200149
Validation Data：Presence

A IRES-Cre expression cassette was knocked into the Emx1 gene stop codon site.

Mice

hMASP2

Strain Name：C57BL/6Smoc-Masp2tm1(hMASP2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000076
Validation Data：Presence

The endogenous mouse Masp2 gene was replaced by human MASP2 gene.

Mice

Il33-KO(2)

Strain Name：C57BL/6Smoc-Il33em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190436
Validation Data：Presence  |  Publications：1piece

Il33-KO(2) mice(Stock No.NM-KO-190436) carry a knockout allele derived from the targeted deletion of exon 3-7. While Il33-KO mice(Stock No.NM-KO-00099) have been pulled from shelves for some reasons and Il33-KO(3) mice(Stock No.NM-KO-210206) carrying the exon 2 deletion.

Mice

Wnt1-Dre

Strain Name：C57BL/6Smoc-Wnt1em1(Dre-Wpre-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200176
Validation Data：Presence

A Dre-Wpre-polyA expression cassette was knocked into the Wnt1 gene start codon site. Wnt1 gene is involved in stem cell poliferation in multiple systems, including the hematopoietic system and the embryonic nervous system. This strain may be useful for studying central nervous system development. When crossed with a strain carrying a gene flanked by rox sites, the flanked gene will be removed in cells expressing dre.

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