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Models

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Mice

hAPOE4

Strain Name：C57BL/6Smoc-Apoetm2(hAPOE4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190002

This APOE4 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE4 corresponding sequence by homologous recombination.

Mice

hICOSL

Strain Name：C57BL/6Smoc-Icoslem1(hICOSLG) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00095

The endogenous mouse Icosl gene was replaced by human ICOSL gene . While hICOSL(2)(Stock No.NM-HU-2000068) mice function similarly to hICOSL mice,for more detailed information please contact our technical advisor.

Mice

hIL4RA

Strain Name：C57BL/6Smoc-Il4ratm1(hIL4R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190008

The endogenous mouse Il4ra gene was replaced by human IL4R gene.

Mice

hTNFSF14

Strain Name：C57BL/6Smoc-Tnfsf14tm1(hTNFSF14)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225069

The endogenous mouse Tnfsf14 gene was replaced by human TNFSF14 gene.

Mice

Il1a-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il1aem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00009

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon.

Mice

Angptl6-KO

Strain Name：C57BL/6Smoc-Angptl6em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201240

Exon 3 of Angptl6 gene was deleted to generate Angptl6 knockout mice.

Mice

Cartpt-IRES-Cre

Strain Name：C57BL/6Smoc-Cartptem1(IRES-iCre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200094

A IRES-iCre expression cassette was knocked into the Cartpt gene stop codon site.

Mice

hCD40/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Cd40em1(hCD40)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210406

hPD-1/hPD-L1(NM-HU-00100) was crossed with hCD40（NM-HU-00076）to generate hCD40/hPD-1/hPD-L1 mice

Mice

hIL1B

Strain Name：C57BL/6Smoc-Il1btm3(hIL1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190047

The endogenous mouse Il1b gene was replaced by human IL1B gene.

Mice

Col1a2-2A-DreERT2

Strain Name：C57BL/6Smoc-Col1a2em1(2A-DreERT2-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210109

2A-DreERT2-Wpre-pA expression cassette was knocked into the Col1a2 gene .

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