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Models

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Mice

Lyz2-2A-CreERT2

Strain Name：C57BL/6Smoc-Lyz2em1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18018

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

Cck-IRES-Cre

Strain Name：C57BL/6Smoc-Cckem1(IRES-iCre-PolyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200131

A IRES-iCre-PolyA expression cassette was knocked into the Cck gene stop codon site.

Mice

hAPOE2

Strain Name：C57BL/6Smoc-Apoetm4(hAPOE2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190013

This APOE2 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE2 corresponding sequence by homologous recombination.

Mice

hTNFRSF10B

Strain Name：C57BL/6Smoc-Tnfrsf10bem1(hTNFRSF10B)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210005

The endogenous mice Tnfrsf10B gene was replaced by human TNFRSF10B gene

Mice

Ucp1-CreERT2

Strain Name：C57BL/6Smoc-Ucp1em1(Kozak-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190102

A Kozak-CreERT2-WPRE-polyA expression cassette was knocked into the Ucp1 gene start codon site.

Mice

Drd2-KO

Strain Name：C57BL/6Smoc-Drd2em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190265

This Drd2 knockout mouse model was generated by knocking out the exon 3 region of the Drd2.

Mice

hIL4/hIL4R

Strain Name：C57BL/6Smoc-Il4tm3(hIL4)Il4ratm1(hIL4R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000106

These mice are obtained through breeding of two single gene humanized mice.

Mice

Abcg2-KO

Strain Name：C57BL/6Smoc-Abcg2em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18013

Exon3-5 of Abcg2 gene were deleted to generate Abcg2 knockout mice.

Mice

Ifnar1-KO

Strain Name：C57BL/6Smoc-Ifnar1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18038

The Ifnar1 knockout mouse model was obtained by knocking out the exon 3-11 region of mouse Ifnar1 gene.

Mice

hCD52

Strain Name：C57BL/6Smoc-Cd52em1(hCD52)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000058

The endogenous mouse Cd52 gene was replaced by human CD52 gene.

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