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Models

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Mice

hCD3E/hCD20(2)

Strain Name:C57BL/6Smoc-Cd3etm1(hCD3E)Ms4a1tm2(hCD20)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220035

hCD3E(NM-HU-00114) mice were crossed with hCD20(2)(NM-HU-200114) to generate hCD3E/hCD20(2) mice.

Mice

hTNFSF14

Strain Name:C57BL/6Smoc-Tnfsf14tm1(hTNFSF14)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225069

The endogenous mouse Tnfsf14 gene was replaced by human TNFSF14 gene.

Mice

hSIGLEC8(2)

Strain Name:C57BL/6Smoc-Siglecftm1(hSIGLEC8)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210033
Validation Data:Presence

The endogenous mice Siglecf gene was replaced by human SIGLEC8 gene. While hSIGLEC8(Stock No.NM-HU-204983) mice function similarly to hSIGLEC8(2) mice,for more detailed information please contact our technical advisor.

Mice

Ikzf3-KO

Strain Name:C57BL/6Smoc-Ikzf3em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-2104251

Exon 8 of Ikzf3 gene was deleted to generate Ikzf3 knockout mice.

Mice

hSOST

Strain Name:C57BL/6Smoc-Sosttm1(hSOST)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200251
Validation Data:Presence

The endogenous mice Sost gene was replaced by human SOST gene. While hSOST(2)(Stock No.NM-HU-215021) mice function similarly to hSOST mice, for more detailed information please contact our technical advisor.

Mice

R26-LSL-hIL15-Flag-IRES-EGFP

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sortm(CAG-Loxp-Stop-Loxp-Kozak-hIL2 signal peptide-hIL15-Flag-IRES-EGFP-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-220130

CAG-Loxp-Stop-Loxp-Kozak-hIL2 signal peptide-hIL15-Flag-IRES-EGFP-polyA expression cassette was knocked into the the Rosa26 locus

Mice

hIL1RL1

Strain Name:C57BL/6Smoc-Il1rl1tm4(hIL1RL1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-2000067
Validation Data:Presence

The endogenous mouse Il1rl1 gene was replaced by human IL1RL1 gene.

Mice

hPD-1/hTIGIT

Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1) Tigittm1(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00104

hPD-1(NM-HU-00015) was crossed with hTIGIT(NM-HU-00053) to generate hPD-1/hTIGIT.

Mice

Axin2-2A-DreERT2

Strain Name:C57BL/6Smoc-Axin2em1(P2A-DreERT2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200196
Validation Data:Presence

A P2A-DreERT2 expression cassette was knocked into the Axin2 gene stop codon site.

Mice

hCD45

Strain Name:C57BL/6Smoc-Ptprctm1(hPTPRC)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225080
Validation Data:Presence

The endogenous mouse Ptprc gene was replaced by human PTPRC gene.

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