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Models

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Mice

hGPRC5D

Strain Name：C57BL/6Smoc-Gprc5dtm1(hGPRC5D)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215058
Validation Data：Presence

The endogenous mouse Gprc5d gene was replaced by human GPRC5D gene.

Mice

Nmu-2A-Cre

Strain Name：C57BL/6Smoc-Nmuem1(2A-Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200298
Validation Data：Presence

2A-Cre-WPRE-polyA expression cassette was knocked into the Nmu gene stop codon site. Nmu gene encodes a member of the neuromedin family of neuropeptides. The encoded protein plays a role in energy homeostasis and body temperature regulation. And the protein is homologous with human NMU, which is linked toobesity.

Mice

hPD-L1/hOX40

Strain Name：C57BL/6Smoc-Cd274tm1(hPD-L1)Tnfrsf4tm1(hTNFRSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00111

hPD-L1（NM-HU-00062）was crossed with hOX40（NM-HU-00041）to generate hPD-L1/hOX40.

Mice

hCD4

Strain Name：C57BL/6Smoc-Cd4tm1(hCD4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00115
Validation Data：Presence

The endogenous mouse Cd4 gene was replaced by human CD4 gene .

Mice

Lyz2-IRES-mtagBFP2-Luc

Strain Name：C57BL/6Smoc-Lyz2em4(IRES-mtagBFP-Luci)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200029
Validation Data：Presence

A IRES-mtagBFP-luci expression cassette was knocked into the Lyz2 gene stop codon site.

Mice

Agrp-Dre

Strain Name：C57BL/6Smoc-Agrpem(Kozak-Dre-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220331

Kozak-Dre-WPRE-pA expression cassette was knocked into the Agrp gene start codon site.

Mice

Alpl-KO

Strain Name：C57BL/6Smoc-Alpltm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18058
Validation Data：Presence

This Alpl knockout mouse model was obtained by knocking out the exon 3-4 region of the Alpl gene.

Mice

Tyro3-KO

Strain Name：C57BL/6Smoc-Tyro3em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200558

Exon 3 of Tyro3 gene was deleted to generate Tyro3 knockout mice.

Mice

Cdh5-2A-CreERT2

Strain Name：C57BL/6Smoc-Cdh5em1(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200173
Validation Data：Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Cdh5 gene stop codon site.

Mice

hPD-L1/hCD73(2)

Strain Name：C57BL/6Smoc-Cd274tm1(hPD-L1)Nt5etm2(NT5E)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210356

hPD-L1(NM-HU-00062) was crossed with hCD73(2)(NM-HU-200009) to generate hPD-L1/hCD73(2) mice.

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