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Models

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Mice

hIL17A

Strain Name：C57BL/6Smoc-Il17atm1(hIL17A)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00042
Validation Data：Presence

The endogenous mouse Il17a gene was replaced by human IL17A gene.

Mice

Foxn1-IRES-Cre

Strain Name：C57BL/6Smoc-Foxn1em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200106
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Foxn1 gene stop codon site. The protein encoded by Foxn1 (forkhead box N1) gene is part of the forkhead family or transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in thymic epithelial cell and keratinocytes.

Mice

hVEGFA

Strain Name：C57BL/6Smoc-Vegfatm2(hVEGFA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000028
Validation Data：Presence

The endogenous mouse Vegfa gene was replaced by human VEGFA gene. While hVEGFA(2)(Stock No.NM-HU-204984) mice function similarly to hVEGFA mice,for more detailed information please contact our technical advisor.

Mice

hEGFR

Strain Name：C57BL/6Smoc-Egfrtm1(hEGFR)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200227
Validation Data：Presence

The endogenous mice Egfr gene was replaced by human EGFR gene. While hEGFR(2)(Stock No.NM-HU-200232) mice have been pulled from shelves for some reasons.

Mice

hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00100
Validation Data：Presence

hPD-1(NM-HU-00015) was crossed with hPD-L1(NM-HU-00062)to generate hPD-1/hPD-L1 mice

Mice

Pten-Flox

Strain Name：C57BL/6Smoc-Ptenem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-18004
Publications：1piece

These Pten flox mice possess loxP sites flanking exons 5 via CRISPR/Cas mediated recombination. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

hTLR7

Strain Name：C57BL/6Smoc-Tlr7tm1(hTLR7)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18027
Validation Data：Presence

The endogenous mouse Tlr7 gene was replaced by humanTLR7 gene.

Mice

hCD27(2)/hFCGR2B

Strain Name：C57BL/6Smoc-Cd27tm3(hCD27)Fcgrt2btm2(hFCGRT2B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210405

hCD27(2) (NM-HU-190035) was crossed with hFCGR2B (NM-HU-2000010) to generate hCD27(2)/hFCGR2B mice.

Mice

Abcd1-KO

Strain Name：C57BL/6Smoc-Abcd1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2106014

Exon 2 of Abcd1 gene was deleted to generate Abcd1 knockout mice.

Mice

Cx3cr1-CreERT2

Strain Name：C57BL/6Smoc-Cx3cr1em1(creERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200157
Validation Data：Presence

A creERT2-WPRE-polyA expression cassette was knocked into the Cx3cr1 gene start codon site.

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