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Models

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Mice

Abcc2-KO

Strain Name：C57BL/6Smoc-Abcc2em3Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18017

Exon4-6 of Abcc2 gene were deleted to generate Abcc2 knockout mice.

Mice

MHC ClassII(I-A/I-E)-KO(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1H2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-ps em1Smoc
Strain State：Developing | Cat. NO.：NM-NSG-003

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the NMG genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

Gp1ba-2A-Cre

Strain Name：C57BL/6Smoc-Gp1baem1(T2A-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200172
Validation Data：Presence

A T2A-iCre expression cassette was knocked into the Gp1ba gene stop codon site.

Mice

Itgam-IRES-hCD89

Strain Name：C57BL/6Smoc-Itgamtm1(IRES-hCD89-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200063
Validation Data：Presence  |  Publications：1piece

A IRES-hCD89-WPRE-polyA expression cassette was knocked into the Itgam gene stop codon site.

Mice

Isl1-Dre

Strain Name：C57BL/6Smoc-Isl1em1(Dre-Wpre-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200177

A Dre-Wpre-polyA expression cassette was knocked into the Isl1 gene start codon site.

Mice

Ins2-CreERT2

Strain Name：C57BL/6Smoc-Ins2em(CreERT2)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225022
Validation Data：Presence

CreERT2 expression cassette was knocked into the Ins2 gene .

Mice

hCD3EDG/hCD40/h4-1BB(2)

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd40tm1(hCD40)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220117

hCD3EDG/hCD40(NM-HU-220116) mice were crossed with hCD3EDG/h4-1BB(2)(NM-HU-220110) to generate hCD3EDG/hCD40/h4-1BB(2) mice.

Mice

Hif1a-Flox

Strain Name：C57BL/6Smoc-Hif1atm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-190065
Publications：1piece

These mice carry loxP sites flanking exon 2 of Hif1a gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Hif1a gene.

Mice

hCD3EDG/h4-1BB(2)

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220110

hCD3EDG(NM-HU-220120) mice were crossed with h4-1BB(2)(NM-HU-190077) to generate hCD3EDG/h4-1BB(2) mice.

Mice

hNCR2

Strain Name：C57BL/6Smoc-Ncr1tm1(hNCR2 )Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215068

The endogenous mouse Ncr1 gene was replaced by human NCR2 gene.

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