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Models

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Mice

Clec4f-IRES-Cre-2A-tdTomato

Strain Name：C57BL/6Smoc-Clec4fem1(IRES-iCre-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200069
Validation Data：Presence

A IRES-iCre-2A-tdTomato expression cassette was knocked into the Clec4f gene stop codon site.

Mice

MHCII/B2m-KO(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1H2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-ps em1B2m em1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-014

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models.Also, B2m gene was knocked out. These MHC class I and II molecule-deficient mice were on the NMG genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins and B2m of class I.

Mice

Agr2-2A-CreERT2(2)

Strain Name：C57BL/6Smoc-Agr2em1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-231956

The 2A-CreERT2-WPRE-pA expression cassette was knocked into the Agr2 gene stop codon site.

Mice

R26-CAG-LSL-hFGFR2-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(SA-2xpolyA-CAG-LSL-FGFR2-luciferase-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190007

A SA-2xpolyA-CAG-LSL-FGFR2-IRES-luciferase-2A-EGFP-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the FGFR2 protein.

Mice

Tsc1-Flox

Strain Name：C57BL/6Smoc-Tsc1tm1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200231

These mice carry loxP sites flanking exon 17-18 of Tsc1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Tsc1 gene.

Mice

Osr2-IRES-CreERT2

Strain Name：C57BL/6Smoc-Osr2em(IRES-CreERT2-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215086

IRES-CreERT2-Wpre-pA expression cassette was knocked into the Osr2 gene .

Mice

hPD-1/hVEGFR2

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Kdrtm2(hKDR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000098

hPD-1(NM-HU-00015) was crossed with hKDR(NM-HU-00098) to generate hPD-1/hKDR.

Mice

Wap-IRES-Cre

Strain Name：C57BL/6Smoc-Wapem1(IRES-Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200064
Validation Data：Presence

A IRES-Cre-WPRE-polyA expression cassette was knocked into the Wap gene stop codon site.

Mice

Dot1l-Flox

Strain Name：C57BL/6Smoc-Dot1lem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253748

These mice carry loxP sites flanking exon 2 of Dot1l gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dot1l gene.

Mice

Aard-Flox

Strain Name：C57BL/6Smoc-Aardem1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-260844

These mice carry loxP sites flanking exon1-2 of Aard gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aard gene.

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