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Models

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Mice

hIL2

Strain Name：C57BL/6Smoc-Il2tm3(hIL2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190048
Validation Data：Presence

The endogenous mouse Il2 gene was replaced by human IL2 gene.

Mice

Il17c-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il17cem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00030

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il17c.

Mice

R26-CAG-LSL-hIDH2*R140Q-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190075

These mice harbor a CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

Rag1-KO

Strain Name：C57BL/6Smoc-Rag1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-252600

The exon 2 of Rag1 gene was deleted to generate Rag1 knockout mouse.

Mice

hPD-1/hPD-L1/hCD47/hSIRPA(BALB/c)

Strain Name：BALB/cAnSmoc-Pdcd1tm(hPDCD1)Cd274tm(hPD-L1)Sirpatm4(hSIRPA)Cd47tm1(hCD47)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220143

hSIRPA/hCD47(BALB/c)(NM-HU-210020) mice was crossed with hPD-1/ hPD-L1(BALB/c)(NM-HU-220142) mice to generate hPD-1/hPD-L1/hCD47/hSIRPA(BALB/c) mice.

Mice

Slc6a1-KO

Strain Name：B6;129S-Slc6a1tm1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-00002

Slc6a1-KO mice(Stock No.NM-KO-00002）carry a knockout allele derived from the targeted deletion of exon 2-3. While Slc6a1-KO(2) mice (Stock No.NM-KO-210290）carrying the exon 6 deletion. Slc6a1-KO(3) mice(Stock No.NM-KO-210126） carrying the exon 7 deletion.

Mice

Aadacl2-Flox

Strain Name：C57BL/6Smoc-Aadacl2em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253928

These mice carry loxP sites flanking exon 2 of Aadacl2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadacl2 gene.

Mice

Cela1-2A-DreERT2

Strain Name：C57BL/6Smoc-Cela1em1(2A-DreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190094
Validation Data：Presence  |  Publications：1piece

A 2A-DreERT2 expression cassette was knocked into the Cela1 gene stop codon site.

Mice

A4gnt-KO

Strain Name：C57BL/6Smoc-A4gntem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-201369

Exon 2-3 of A4gnt gene was deleted to generate A4gnt knockout mice.

Mice

Dbt-KO

Strain Name：C57BL/6Smoc-Dbtem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200633

Exon 2 of Dbt gene was deleted to generate Dbt knockout mice.

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