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Models

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Mice

hITGAV

Strain Name：C57BL/6Smoc-Itgavem1(hITGAV)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225043

The endogenous mouse Itgav gene was replaced by human ITGAV gene.

Mice

hIL12RB2

Strain Name：C57BL/6Smoc-Il12rb2tm(hIL12RB2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215019

The endogenous mouse Il12rb2 gene was replaced by human IL12RB2 gene.

Mice

MHC Class II (I-A/I-E) -KO

Strain Name：C57BL/6Smoc-H2-Ab1em1H2-Aaem1 H2-Eb1em1H2-Eb2em1H2-Ea-ps em1 Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18032

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the C57BL/6J genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

Cd207-2A-CreERT2

Strain Name：C57BL/6Smoc-Cd207em2(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200021

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Cd207 gene stop codon site.

Mice

Bag3-Flox

Strain Name：C57BL/6Smoc-Bag3em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-2101856

These mice carry loxP sites flanking exon 4 of Bag3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Bag3 gene.

Mice

hSIRPA(2)/hCD47/hPD-1/hPD-L1(2)

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Pdcd1em1(hPDCD1)Cd274em2(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220029

hSIRPA(2)(NM-HU-18015), hCD47(NM-HU-00050) and hPD-1(NM-HU-00015) was crossed with hPD-L1(2)(NM-HU-190039）to generate hSIRPA(2)/hCD47/hPD-1/hPD-L1(2) mice.

Mice

Npr3-2A-DreERT2

Strain Name：C57BL/6Smoc-Npr3em1(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190015

The 2A-DreERT2 cassette is inserted before 3'UTR region of Npr3 gene.

Mice

Siglecf-DreERT2

Strain Name：C57BL/6Smoc-Siglecfem1(kozak-DreER-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200202

A kozak-DreER-WPRE-pA expression cassette was knocked into the Siglecf gene start codon site.

Mice

Il1f10-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il1f10em1(Luc-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00060

A Luciferase-2a-egfp-polyA cassette was inserted at ATG site of mouse Il1f10 gene.

Mice

Il7-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il7em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00092

A Luciferase-2a-egfp-polyA cassette was inserted at ATG site of mouse Il7 gene.

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