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Models

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Mice

hIL3/hCSF2

Strain Name：C57BL/6Smoc-Il3tm3(hIL3)Csf2tm3(hCSF2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190065

The endogenous mouse Il3 and Csf2 gene was replaced by human IL3 and CSF2 gene.

Mice

Foxp3-DreERT2

Strain Name：C57BL/6Smoc-Foxp3em5(IRES-DreER)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200198

A IRES-DreER expression cassette was knocked into the Foxp3 gene stop codon site.

Mice

Ptf1a-CreERT2

Strain Name：C57BL/6Smoc-Ptf1aem1(CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200118

A CreERT2-WPRE-pA expression cassette was knocked into the Ptf1a gene start codon site.

Mice

hIL1RL2

Strain Name：C57BL/6Smoc-Il1rl2em1(hIL1RL2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215057

The endogenous mouse Il1rl2 gene was replaced by human IL1RL2 gene.

Mice

hNR1I2

Strain Name：C57BL/6Smoc-Nr1i2em3(hNR1I2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000066

The endogenous mouse Nr1i2 gene was replaced by human NR1I2 gene.

Mice

hMARCO

Strain Name：C57BL/6Smoc-Marcoem1(hMARCO)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000029

The endogenous mouse Marco gene was replaced by human MARCO gene.

Mice

Atp4b-IRES-CreERT2(2)

Strain Name：C57BL/6Smoc-Atp4bem2(IRES-CreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210119

An IRES-CreERT2 expression cassette was knocked into the Atp4b gene stop codon site. Besides,An IRES-CreERT2-WPRE-pA expression cassette were knock into the Atp4b gene start codon site to generate Atp4b-IRES-CreERT2(Stock No. NM-KI-210118) mice. ATP4B could serve as a tumor suppressor in the tumorigenesis and progression. This strain is useful in studying the function of gastric parietal cells in gastric epithelial homeostasis. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cre-expressing cells after tamoxifen treatment.

Mice

hCTLA-4(2)

Strain Name：C57BL/6Smoc-Ctla4em2(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190038

Extracellular domain of mouse Ctla4 gene was replaced by human CTLA4 gene. While hCTLA4(Stock No.NM-HU-00014) mice function similarly to hCTLA4(2) mice,for more detailed information please contact our technical advisor.

Mice

Tyro3-KO

Strain Name：C57BL/6Smoc-Tyro3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200558

Exon 3 of Tyro3 gene was deleted to generate Tyro3 knockout mice.

Mice

Il34-Luc-2A-EGFP

Strain Name：B6;129S-Il34tm1(Luc-eGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00035

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il34.

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