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Models

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Mice

Krt5-IRES-CreERT2

Strain Name：C57BL/6Smoc-Krt5em1(IRES-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200168

A IRES-CreERT2 expression cassette was knocked into the Krt5 gene stop codon site.

Mice

Isl1-Dre

Strain Name：C57BL/6Smoc-Isl1em1(Dre-Wpre-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200177

A Dre-Wpre-polyA expression cassette was knocked into the Isl1 gene start codon site.

Mice

hFOXP2

Strain Name：C57BL/6Smoc-Foxp2em1(hFOXP2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210002

The endogenous mice Foxp2 gene was replaced by human FOXP2 gene

Mice

Lepr-KO

Strain Name：C57BL/6Smoc-Leprem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190663

Exon 5 of Lepr gene was deleted to generate Lepr knockout mice.

Mice

R26-pAlb-TK-IRES-Luc-2A-EGFP(NOD-scid)

Strain Name：NOD-PrkdcscidGt(ROSA)26Sorem1(Alb-TK-IRES-luc-2A-EGFP-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18040

These Nod-Scid mice harbor a cassette containing Alb promoter-TK-IRES-luciferase-2A-EGFP-polyA. The targeted mutation was inserted into the Gt(ROSA)26Sor locus.

Mice

Cd79a-2A-Cre

Strain Name：C57BL/6Smoc-Cd79aem(2A-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220089

2A-Cre expression cassette was knocked into the Cd79a gene stop codon site.

Mice

hIGHA1

Strain Name：C57BL/6Smoc-sμtm1(hIGHA1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000086

The endogenous mouse sμ region was replaced by human IGHA1.

Mice

Pax7-IRES-Cre

Strain Name：C57BL/6Smoc-Pax7em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200120

A IRES-iCre expression cassette was knocked into the Pax7 gene stop codon site. Pax7 is expressed in myogenic progenitor cells. Pax7 is essential for the myogenic potential, survival, and proliferation of myogenic progenitors. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Pax7.

Mice

Myf5-Cre

Strain Name：C57BL/6Smoc-Myf5em1(Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200147

A Cre-WPRE-polyA expression cassette was knocked into the Myf5 gene start codon site. Myogenic factor 5 (Myf5) belongs to the MRF family transcription factors that regulate myogenesis. It is expressed in the skeletal muscle and satellite cells. Severe loss of skeletal muscle following ablation of Myf5-expressing progenitors. This strain is useful in studying the differentiation of skeletal muscle.

Mice

Ikzf3-KO

Strain Name：C57BL/6Smoc-Ikzf3em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2104251

Exon 8 of Ikzf3 gene was deleted to generate Ikzf3 knockout mice.

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