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Models

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Mice

Itgam-IRES-DTRGFP

Strain Name：C57BL/6Smoc-Itgamem1(IRES-DTR-EGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200066
Validation Data：Presence

A IRES-DTR-EGFP expression cassette was knocked into the Itgam gene stop codon site.

Mice

Nkx3-1-IRES-CreERT2

Strain Name：C57BL/6Smoc-Nkx3-1em1(IRES-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200071
Validation Data：Presence

A IRES-CreERT2 expression cassette was knocked into the Nkx3-1 gene stop codon site.

Mice

Procr-DreERT2

Strain Name：C57BL/6Smoc-Procrem1(kozak-DreER-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200201

A kozak-DreER-WPRE-pA expression cassette was knocked into the Procr gene start codon site.

Mice

hPD-1/hCD40

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd40tm1(hCD40)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190017

hPD-1(NM-HU-00015) was crossed with hCD40(NM-HU-00076) to generate hPD-1/hCD40.

Mice

Aadacl2fm1-KO

Strain Name：C57BL/6Smoc-Aadacl2fm1em1Smoc
Strain State：Developing | Cat. NO.：NM-KO-261270

The exon 5 of Aadacl2fm1 gene was deleted to generate Aadacl2fm1 knockout mouse.

Mice

Stra8-2A-tdTomato-2A-Cre

Strain Name：C57BL/6Smoc-Stra8em(T2A-tdTomato-P2A-Cre)1Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225030
Validation Data：Presence

T2A-tdTomato－P2A－Cre expression cassette was knocked into the Stra8 gene .

Mice

hOX40/hCTLA-4

Strain Name：C57BL/6Smoc-Tnfrsf4tm3(hTNFRSF4)Ctla4tm1(hCTLA4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00105

These mice are OX40 and CTLA4 double knockin mouse models which can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

Aadacl4fm1-Flox

Strain Name：C57BL/6Smoc-Aadacl4fm1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253852

These mice carry loxP sites flanking exon 2 of Aadacl4fm1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadacl4fm1 gene.

Mice

Slc32a1-IRES-Cre

Strain Name：C57BL/6Smoc-Slc32a1em1(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200081
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Slc32a1 gene stop codon site.

Mice

Aacs-KO

Strain Name：C57BL/6Smoc-Aacsem1Smoc
Strain State：Developing | Cat. NO.：NM-KO-261269

The exon 2 of Aacs gene was deleted to generate Aacs knockout mouse.

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