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Models

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Mice

hTPBG

Strain Name：C57BL/6Smoc-Tpbgem1(hTPBG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200239

The endogenous mice Tpbg gene was replaced by human TPBG gene.

Mice

hLILRB4

Strain Name：C57BL/6Smoc-Lilrb4aem1(hLILRB4 )Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210024

The endogenous mice Lilrb4a gene was completely or partially replaced by human LILRB4 gene via CRISPR/Cas9 mediated recombination.

Mice

hGNRHR

Strain Name：C57BL/6Smoc-Gnrhrem(hGNRHR)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220137

The endogenous mouse Gnrhr gene was replaced by human GNRHR gene.

Mice

Ifng-Venus-Luc

Strain Name：C57BL/6Smoc-Ifngem1(IRES-Venus-Luci)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18041

An IRES-Venus-Luci co-expression cassette was inserted in 3'UTR region of Ifng gene.

Mice

Glp1r-IRES-Cre

Strain Name：C57BL/6Smoc-Glp1rem1(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200134

A IRES-iCre expression cassette was knocked into the Glp1r gene stop codon site.

Mice

Car4-DreERT2

Strain Name：C57BL/6Smoc-Car4em1(DreERT2-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200193

A DreERT2-Wpre-pA expression cassette was knocked into the Car4 gene start codon site.

Mice

hIL21/hIL21R

Strain Name：C57BL/6Smoc-Il21tm1(hIL21)Il21rtm1(hIL21R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220038

hIL21(NM-HU-200255) were crossed with hIL21R(NM-HU-210031) to generate hIL21/hIL21R mice.

Mice

R26-CAG-LSL-hPIK3CA*H1047R-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190065

These mice harbor a CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

C1qa-KO

Strain Name：C57BL/6Smoc-C1qaemSmoc
Strain State：Repository Live | Cat. NO.：NM-KO-210110

exon 3 of C1qa gene was deleted to generate C1qa knockout mice.

Mice

Il17a-Cre

Strain Name：C57BL/6Smoc-Il17aem1(iCre-polyA(SV40))Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200137

A iCre-polyA expression cassette was knocked into the Il17a gene start codon site. This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying autoimmune inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis.

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