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Models

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Mice

hSERPINC1

Strain Name：C57BL/6Smoc-Serpinc1tm1(hSERPINC1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225075

The endogenous mouse Serpinc1 gene was replaced by human SERPINC1 gene.

Mice

hIL18BP

Strain Name：C57BL/6Smoc-Il18bpem1(hIL18BP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210039

The endogenous mice Il18bp gene was replaced by human IL18BP gene.

Mice

Gad1-2A-eGFP

Strain Name：C57BL/6Smoc-Gad1em(2A-eGFP)Smoc
Strain State：Developing | Cat. NO.：NM-KI-220179

2A-eGFP expression cassette was knocked into the Gad1 gene stop codon site.

Mice

Scgb1a1-IRES-CreERT2

Strain Name：C57BL/6Smoc-Scgb1a1em1(IRES-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200129

A IRES-CreERT2 expression cassette was knocked into the Scgb1a1 gene stop codon site.

Mice

hPD-L1(BALB/c)

Strain Name：BALB/cAnSmoc-Cd274em(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220028

The hPD-L1(NM-HU-00062) mice were backcrossed to BALB/c genetic background, to create the new strain of hPD-L1(BALB/c) (NM-HU-220028) mice.

Mice

hLAG3/hCTLA-4

Strain Name：B6.129S-Lag3tm1(hLAG3)Ctla4em1(hCTLA4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190018

This LAG3 and CTLA4 double knockin strain is established by crossing LAG3-HU and CTLA4-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

Krt5-2A-CreERT2

Strain Name：C57BL/6Smoc-Krt5em1(2A-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190016

The 2A-CreERT2 cassette is inserted before 3'UTR region of Krt5 gene.

Mice

H2/H2-K1-KO(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1h2em2H2-K1em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-NSG-006

Exon 2 of H2;H2-K1 gene was deleted to generate H2;H2-K1 knockout mice.

Mice

hIL7(BALB/c)

Strain Name：BALB/cAnSmoc-Il7tm1(hIL7)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220014

The endogenous mouse Il7r gene was replaced by human IL7R gene.

Mice

hDMD

Strain Name：C57BL/6Smoc-Dmdtm1(hDMD)Smoc
Strain State：Developing | Cat. NO.：NM-HU-225088

The endogenous mouse Dmd gene was replaced by human DMD gene.

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