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Models

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Mice

C4b-KO

Strain Name：C57BL/6Smoc-C4bem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190761

Exon 3 of C4b gene was deleted to generate C4b knockout mice.

Mice

hPD-1/hVISTA

Strain Name：C57BL/6Smoc-Visrtm1(hVSIR)Pdcd1tm1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000092

hPD-1(NM-HU-00015) was crossed with hSIRPA(2) (NM-HU-18015) to generate hPD-1/hVISTA.

Mice

Esr1-2A-Cre

Strain Name：C57BL/6Smoc-Esr1em1(2A-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200164
Validation Data：Presence

A 2A-iCre expression cassette was knocked into the Esr1 gene stop codon site.

Mice

Foxp3-V5-AviTag-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Foxp3em1(V5-AviTag-IRES-luci-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18034

A V5-AviTag-IRES-luci-2A-tdTomato expression cassette was inserted before the stop codon TGA of mouse Foxp3 gene to establish a multi-labeled knockin model with V5, Avi, luciferase and tdTomato fluorescent protein.

Mice

hTPBG

Strain Name：C57BL/6Smoc-Tpbgtm1(hTPBG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200239
Validation Data：Presence

The endogenous mice Tpbg gene was replaced by human TPBG gene.

Mice

hPD-1/hPD-L1/hTIM3

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Havcr2tm1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200264

hTIM3（NM-HU-00054）,hPD-1（NM-HU-00015）,hPD-L1（NM-HU-00062）were crossed together to generate hPD-1/hPD-L1/hTIM3 mice

Mice

hIL12RB2

Strain Name：C57BL/6Smoc-Il12rb2tm(hIL12RB2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215019
Validation Data：Presence

The endogenous mouse Il12rb2 gene was replaced by human IL12RB2 gene.

Mice

hIL1RAP

Strain Name：C57BL/6Smoc-Il1raptm3(hIL1RAP)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000070
Validation Data：Presence

The endogenous mouse Il1rap gene was replaced by human IL1RAP gene.

Mice

hPD-L1(2)/hCCR8

Strain Name：C57BL/6Smoc-Cd274tm2(hPD-L1)Ccr8tm1(hCCR8)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210401

hPD-1(2)(NM-HU-190039) was crossed with hCCR8(NM-HU-190053) to generate hPD-L1(2)/hCCR8 mice.

Mice

Aadat-Flox

Strain Name：C57BL/6Smoc-Aadatem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253922

These mice carry loxP sites flanking exon 2 of Aadat gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadat gene.

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