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Models

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Mice

hIL21/hIL21R

Strain Name:C57BL/6Smoc-Il21tm1(hIL21)Il21rtm1(hIL21R)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220038
Validation Data:Presence

hIL21(NM-HU-200255) were crossed with hIL21R(NM-HU-210031) to generate hIL21/hIL21R mice.

Mice

hSIRPA/hCD47(BALB/c)

Strain Name:BALB/cAnSmoc-Sirpatm4(hSIRPA)SmocCd47tm1(hCD47)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210020
Validation Data:Presence

hCD47 (NM-HU-00050) and hSRPA(2)(NM-HU-18015) were bred with BALB/c mice respectively to generate hSIRPA/hCD47(BALB/c) mice.

Mice

Bhlha15-CreERT2

Strain Name:C57BL/6Smoc-Bhlha15em1(CreERT2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200080
Validation Data:Presence

The coding region of Bhlha15 gene was replaced by a CreERT2 expression cassette.Besides,a kozak-CreERT2-WPRE-polyA expression cassette were knock into the Bhlha15 gene start codon site to generate Bhlha15-CreERT2(2)(Stock No. NM-KI-200158) mice. Bhlha15(basic helix-loop-helix family member a15) is also known as Mist1. The gene product is involved in controlling exocrine secretion from the pancreas, small intestine and stomach. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Bhlha15.

Mice

hSIGLEC15

Strain Name:C57BL/6Smoc-Siglec15tm1(hSIGLEC15)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190037
Validation Data:Presence

The endogenous mouse Siglec15 gene was replaced by human SIGLEC15 gene.

Mice

hTROP2

Strain Name:C57BL/6Smoc-Tacstd2tm(hTACSTD2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-215022
Validation Data:Presence

The endogenous mice Tacstd2 gene was replaced by human TACSTD2 gene.

Mice

hICOSL

Strain Name:C57BL/6Smoc-Icosltm1(hICOSLG) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00095
Validation Data:Presence

The endogenous mouse Icosl gene was replaced by human ICOSL gene . While hICOSL(2)(Stock No.NM-HU-2000068) mice function similarly to hICOSL mice,for more detailed information please contact our technical advisor.

Mice

hIL7R

Strain Name:C57BL/6Smoc-Il7rtm1(hIL7R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210027
Validation Data:Presence

The endogenous mice Il7r gene was completely or partially replaced by human IL7R gene via ESC targeting.

Mice

Foxl1-2A-CreERT2

Strain Name:C57BL/6Smoc-Foxl1em1(2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-00135
Validation Data:Presence

A 2A-CreERT2 coexpression cassette is inserted before the stop codon of mouse Foxl1 gene via homologous recombination to establish a Foxl1-CreERT2 recombinase tool stain. This strain can be used to knockout target gene inFoxl1+ cells after tamoxifen treatment when crossed with flox mice.

Mice

Alb-IRES-Cre

Strain Name:C57BL/6Smoc-Albem1(IRES-iCre-WPRE-pA)Smoc
Strain State:Developing | Cat. NO.:NM-KI-200075

A IRES-iCre-WPRE-pA expression cassette was knocked into the Alb gene stop codon site.

Mice

hPSGL-1

Strain Name:C57BL/6Smoc-Selplgtm1(hSELPLG)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00046
Validation Data:Presence

The endogenous mouse Selplg gene was replaced by human SELPLG gene.

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