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Models

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Mice

Gla-KO

Strain Name：C57BL/6Smoc-Glaem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200601
Validation Data：Presence

Exon 2-3 of Gla gene was deleted to generate Gla knockout mice.

Mice

H11-CAG-LSL-hPSEN1-IRES-tdTomato

Strain Name：C57BL/6Smoc-Igs2tm1(CAG-LSL-PSEN1-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190110

These mice harbor a CAG-LSL-PSEN1-IRES-tdTomato-WPRE-polyA cassette in mouse H11 locus via homologous recombination.

Mice

H2-Ab1-Flox

Strain Name：C57BL/6Smoc-H2-Ab1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200183

These mice carry loxP sites flanking exon 1 of H2-Ab1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of H2-Ab1 gene.

Mice

Ces1c-KO

Strain Name：C57BL/6Smoc-Ces1cem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200579

Exon 5 of Ces1c gene was deleted to generate Ces1c knockout mice.

Mice

Cdkn1b-KO

Strain Name：C57BL/6Smoc-Cdkn1bem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200622

Exon 1-2 of Cdkn1b gene was deleted to generate Cdkn1b knockout mice.

Mice

Magi3-KO

Strain Name：C57BL/6Smoc-Magi3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200620

exon4-5 of Magi3 gene was deleted to generate Magi3 knockout mice.

Mice

Pex1-Flox

Strain Name：C57BL/6Smoc-Pex1em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200205

These mice carry loxP sites flanking exon 12-13 of Pex1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Pex1 gene.

Mice

NMG

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-001
Validation Data：Presence  |  Publications：59piece

Prkdc and Il2rg genes were both knocked-out in NOD mice. Lacking mature T, B and NK cells; Low immune rejection against human cells and tissues; Good tumorigenicity so that a small number of cells can form tumors; Significant improvement in the survival of transplanted human cells and tissues; Suitable for the transplantation of human hematopoietic stem cells and the preparation of humanized mouse models; Suitable as the carrier mice for the transplantation of heterologous cells and tissues.

Mice

CAG-hACE2-IRES-Luc-Tg

Strain Name：C57BL/6Smoc-Tgtn(CAG-human ACE2-IRES-Luciferase-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-200002
Validation Data：Presence  |  Publications：2piece

The transgene is composed of a CAG-human ACE2-IRES-Luciferase-WPRE-polyA expression cassette under the control of CAG promter.

Mice

hACE2

Strain Name：C57BL/6Smoc-Ace2tm3(hACE2-flag-Wpre-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200218
Validation Data：Presence  |  Publications：1piece

A human ACE2-flag-Wpre-pA expression cassette was knocked into the Ace2 gene start codon site via CRISPR/Cas9 mediated recombination.

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