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Models

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Mice

Gla-KO

Strain Name：C57BL/6Smoc-Glaem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200601

Exon 2-3 of Gla gene was deleted to generate Gla knockout mice.

Mice

H11-CAG-LSL-hPSEN1-IRES-tdTomato

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-PSEN1-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190110

These mice harbor a CAG-LSL-PSEN1-IRES-tdTomato-WPRE-polyA cassette in mouse H11 locus via homologous recombination.

Mice

H2-Ab1-Flox

Strain Name：C57BL/6Smoc-H2-Ab1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200183

These mice carry loxP sites flanking exon 1 of H2-Ab1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of H2-Ab1 gene.

Mice

Ces1c-KO

Strain Name：C57BL/6Smoc-Ces1cem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200579

Exon 5 of Ces1c gene was deleted to generate Ces1c knockout mice.

Mice

Cdkn1b-KO

Strain Name：C57BL/6Smoc-Cdkn1bem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200622

Exon 1-2 of Cdkn1b gene was deleted to generate Cdkn1b knockout mice.

Mice

Pex1-Flox

Strain Name：C57BL/6Smoc-Pex1em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200205

These mice carry loxP sites flanking exon 12-13 of Pex1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Pex1 gene.

Mice

Magi3-KO

Strain Name：C57BL/6Smoc-Magi3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200620

exon4-5 of Magi3 gene was deleted to generate Magi3 knockout mice.

Mice

NMG

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-001

Prkdc and Il2rg genes were both knocked-out in NOD mice.  Lacking mature T, B and NK cells Low immune rejection against human cells and tissues Good tumorigenicity so that a small number of cells can form tumors. Significant improvement in the survival of transplanted human cells and tissues Suitable for the transplantation of human hematopoietic stem cells and the preparation of humanized mouse models Suitable as the carrier mice for the transplantation of heterologous cells and tissues

Mice

CAG-hACE2-IRES-Luc-Tg

Strain Name：C57BL/6Smoc-Tgtn(CAG-human ACE2-IRES-Luciferase-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-200002

The transgene is composed of a CAG-human ACE2-IRES-Luciferase-WPRE-polyA expression cassette under the control of CAG promter.

Mice

hACE2

Strain Name：C57BL/6Smoc-Ace2em3(hACE2-flag-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-200218

A human ACE2-flag-Wpre-pA expression cassette was knocked into the Ace2 gene start codon site via CRISPR/Cas9 mediated recombination.

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