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Models

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Mice

B2m-hB2M/HLA-A3.1/H2-D1

Strain Name:C57BL/6Smoc-B2mem1(hB2M-linker-HLA-A*0301/H2-D1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-250773

The endogenous mouse B2m gene was replaced by hB2M-linker-HLA-A*0301/H2-D1.

Mice

hCD40

Strain Name:C57BL/6Smoc-Cd40em1(hCD40) Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00076

The endogenous extracellular mouse Cd40 gene was replaced by the extracellular region of human CD40 gene.

Mice

hB7H4

Strain Name:C57BL/6Smoc-Vtcn1em1(hVTCN1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190004

This VTCN1 humanized mouse model was established by replacing the mouse Vtcn1 gene with the human VTCN1. While hB7H4(2)(Stock No.NM-HU-190075) mice function similarly to hB7H4 mice,for more detailed information please contact our technical advisor.

Mice

hBTLA(2)

Strain Name:C57BL/6Smoc-Btlaem2(hBTLA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190040

Extracellular domain of mouse Btla gene was replaced by human BTLA gene. While hBTLA mice(Stock No.NM-HU-18014)have been pulled from shelves for some reasons.

Mice

Fcgr1-KO

Strain Name:C57BL/6Smoc-Fcgr1em1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-18033

The Fcgr1 knockout mouse model was obtained by knocking out all coding regions of mouse Fcgr1 gene.

Mice

hTLR9

Strain Name:C57BL/6Smoc-Tlr9tm1(hTLR9)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-18016

This TLR9 humanized mouse model was established by replacing the mouse Tlr9 gene exon2 with the human TLR9 corresponding sequence by homologous recombination.

Mice

hB7H4(2)

Strain Name:C57BL/6Smoc-Vtcn1em2(hVTCN1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190075

Extracellular domain of mouse Vtcn1 gene was replaced by human VTCN1 gene. While hB7H4(Stock No.NM-HU-190004) mice function similarly to hB7H4(2) mice,for more detailed information please contact our technical advisor.

Mice

Alpl-KO

Strain Name:C57BL/6Smoc-Alpltm1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-18058

This Alpl knockout mouse model was obtained by knocking out the exon 3-4 region of the Alpl gene.

Mice

Cd200-KO

Strain Name:C57BL/6Smoc-Cd200em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190029

This Cd200 knockout mouse model was generated by knocking out the exon 2 region of the Cd200 .

Mice

hAPOE2

Strain Name:C57BL/6Smoc-Apoetm4(hAPOE2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190013

This APOE2 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE2 corresponding sequence by homologous recombination.

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