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Models

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Mice

hIl5

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190001
Validation Data：Presence

This IL5 humanized mouse model was established by replacing the mouse Il5 gene coding exons and introns with the human TLR9 corresponding sequence by homologous recombination.

Mice

hAPOE4

Strain Name：C57BL/6Smoc-Apoetm2(hAPOE4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190002
Validation Data：Presence

This APOE4 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE4 corresponding sequence by homologous recombination.

Mice

hAPOE3

Strain Name：C57BL/6Smoc-Apoetm3(hAPOE3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190003
Validation Data：Presence

This APOE3 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE3 corresponding sequence by homologous recombination.

Mice

Ifnar1-KO

Strain Name：C57BL/6Smoc-Ifnar1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18038

The Ifnar1 knockout mouse model was obtained by knocking out the exon 3-11 region of mouse Ifnar1 gene.

Mice

hCTLA-4(2)

Strain Name：C57BL/6Smoc-Ctla4tm2(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190038

Extracellular domain of mouse Ctla4 gene was replaced by human CTLA4 gene. While hCTLA4(Stock No.NM-HU-00014) mice function similarly to hCTLA4(2) mice,for more detailed information please contact our technical advisor.

Mice

Sirt3-KO

Strain Name：C57BL/6Smoc-Sirt3em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190368

This Sirt3 knockout mouse model was generated by knocking out the exon 2-3 region of the Sirt3.

Mice

1300017j02Rik-KO

Strain Name：C57BL/6Smoc-1300017j02Rikem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190231

This 1300017j02Rik knockout mouse model was generated by knocking out the exon2-12 region of the 1300017j02Rik.

Mice

Lgals3-KO

Strain Name：C57BL/6Smoc-Lgals3em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190107

This Lgals3 knockout mouse model was generated by knocking out the exon 3-4 region of the Lgals3 .

Mice

Prf1-KO

Strain Name：C57BL/6Smoc-Prf1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190193

This Prf1 knockout mouse model was generated by knocking out the exon 3 region of the Prf1.

Mice

Des-KO

Strain Name：C57BL/6Smoc-Desem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190261

This Des knockout mouse model was generated by knocking out the exon 2-5 region of the Des.

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