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Models

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Mice

Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1

Strain Name:C57BL/6Smoc-Fcgr2bem1Fcgr3em1Fcgr4em1Pdcd1em1(hPDCD1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-220068

The Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1 mouse model was obtained by deleting all sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hPD-1(NM-HU-00015) mouse.

Mice

Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1/hCTLA-4

Strain Name:C57BL/6Smoc-Fcgr2bem1Fcgr3em1Fcgr4em1Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-220070

The Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1/hCTLA4 mouse model was obtained by deleting sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hPD-1/hCTLA4(NM-HU-00079) mouse.

Mice

Ighm/Ighd-KO

Strain Name:C57BL/6Smoc-Ighmem1Ighdem1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-200610

Exon 1-6 of Ighm and exon 1-5 of Ighd gene was deleted to generate Ighm and Ighd knockout mice. Homozygous mutant mice lack mature B cells. It may be useful as a model for B cell immunodeficiency found in humans.

Mice

Gpr89/Prkab2-KO

Strain Name:C57BL/6Smoc-Gpr89em1Prkab2em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-18055

The sgRNAs were designed targeting Gpr89 intron11 and Prkab2 intron7 resulting in a sequence deletion of approximately 790 Kb between the Gpr89 gene and the Prkab2 gene.

Mice

Mir29b2/Mir29c-KO

Strain Name:C57BL/6Smoc-Mir29b-2em1 Mir29cem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-00080

Mir29b-2 and Mir29c are located in 3'UTR region of Cd46 gene. a 0.7kb region in length including Mir29b-2 and Mir29c pre-microRNAs was removed in this strain.

Mice

A26c3-Flox

Strain Name:C57BL/6Smoc-A26c3em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD

These mice carry loxP sites flanking target exons of A26c3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A26c3 gene.

Mice

A1bg-Flox

Strain Name:C57BL/6Smoc-A1bgem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD

These mice carry loxP sites flanking target exons of A1bg gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A1bg gene.

Mice

A2m-Flox

Strain Name:C57BL/6Smoc-A2mem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD

These mice carry loxP sites flanking target exons of A2m gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A2m gene.

Mice

A1cf-Flox

Strain Name:C57BL/6Smoc-A1cfem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD

These mice carry loxP sites flanking target exons of A1cf gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A1cf gene.

Mice

A2ml1-Flox

Strain Name:C57BL/6Smoc-A2ml1em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD

These mice carry loxP sites flanking target exons of A2ml1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A2ml1 gene.

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