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Models

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Mice

R26-SA-rtTA

Strain Name：B6;129S-Gt(ROSA)26Sortm1(SA-V5-M2rtTA-FRT-WPRE-FRT-polyA-attb-PGK-Neo-polyA-attp)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18025

These mice harbor a SA-V5-M2rtTA-FRT-WPRE-FRT-polyA-attb-PGK-Neo-polyA-attp expression cassette in mouse Rosa26 loci homologous recombination.

Mice

Il12b-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il12bem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00025

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon.

Mice

Il1a-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il1aem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00009
Validation Data：Presence

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon.

Mice

R26-CAG-LSL-zsGreen

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-zsGreen)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200045
Validation Data：Presence

These mice harbor a CAG-LSL-zsGreen-polyA cassette in the Rosa26 locus generated by homologous recombination.

Mice

hFCRN

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-hFcRn)Fcgrtem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00109
Validation Data：Presence  |  Publications：1piece

This FcRn humanized strain is established by mating endogenous mouse Fcgrt gene Knockout mice with R26-hFcRn(FCGRT) Knock-in mice. These FcRn humanized mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations. While hFCRN(2)(Stock No.NM-HU-190070) and hFCRN(3)(Stock No.NM-HU-2000032）mice function similarly to hFCRN mice,for more detailed information please contact our technical advisor.

Mice

hMASP3

Strain Name：C57BL/6Smoc-Masp1tm1(hMASP3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-231491

The MASP1 gene encodes the MASP3 protein through alternative splicing. This strain was a knock-in model generated by homologous recombination with an hMASP3 cassette at Masp1 gene locus.

Mice

Il9-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il9em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00023

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il9.

Mice

Rag2-KO/hVEGFR2

Strain Name：C57BL/6Smoc-Rag2em1Kdrtm2(hKDR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200280
Validation Data：Presence

The Rag2 gene of NM-HU-00098 was knock out.

Mice

Nectin2-Flox

Strain Name：C57BL/6Smoc-Nectin2em(flox)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-230159

These mice carry loxP sites flanking exon 1 of Nectin2 When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Nectin2 gene.

Mice

Cd24a-Flox

Strain Name：C57BL/6Smoc-Cd24atm1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-210207

These mice carry loxP sites flanking exon 2 of Cd24a gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Cd24a gene.

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