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Models

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Mice

Lyz2-2A-CreERT2

Strain Name：C57BL/6Smoc-Lyz2em1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18018

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

R26-CAG-LNL-CaMPARI

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LNL-CaMPARI)-NSmoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00090

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven CaMPARI gene. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination.

Mice

Tnnt2-dCreERT2

Strain Name：C57BL/6Smoc-Tnnt2em1(rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200015

A rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA expression cassette was knocked into the Tnnt2 gene start codon site.

Mice

Tnni3-dCreERT2

Strain Name：C57BL/6Smoc-Tnni3em1(rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200014

A rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA expression cassette was knocked into the Tnni3 gene start codon site.

Mice

R26-CAG-LNL-Cas9-IRES-Luc

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LNL-Cas9-IRES-Luciferase-pA)
Strain State：Repository Live | Cat. NO.：NM-KI-18002

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Cas9 gene followed by IRES-Luciferase coexpression cassette. The targeted mutation was inserted into the Rosa26 locus by homologous recombination.

Mice

H11-CAG-LSL-hACHE

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-ACHE-WPRE-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00067

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven ACHE gene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. ACHE is expressed when bred to mice that express Cre recombinase.

Mice

Cyp2e1-DreERT2

Strain Name：C57BL/6Smoc-Cyp2e1em1(DreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18010

A 2A-DreERT2-wpre-polyA coexpression cassette is inserted before the stop codon of mouse Cyp2e1 gene via homologous recombination to establish a Cyp2e1-DreERT2 recombinase tool stain. This strain can be used to knockout target gene in Cyp2e1+ cells afte

Mice

R26-LSL-PhiC31

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-PhiC31)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-00088

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven PhiC31 gene. The targeted mutation was inserted into the Gt(ROSA)26Sor locus.

Mice

R26-CAG-LNL-Fen1-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LNL-Fen1-3XHA-IRES-EGFP-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00126

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Fen1 gene followed by 3xHA-IRES-EGFP tag coexpression cassette. The targeted mutation was inserted into the Rosa26 locus by homologous recombination.

Mice

R26-Renilla-Luc

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-Renilla-Luc)-NSmoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00091

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Renilla-Luc gene. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination.

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