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Models

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Mice

Cdh8-KO

Strain Name：C57BL/6Smoc-Cdh8em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190934

Exon 6 of Cdh8 gene was deleted to generate Cdh8 knockout mice.

Mice

Il34-KO

Strain Name：C57BL/6Smoc-Il34em2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190501

Exon 3 of Il34 gene was deleted to generate Il34 knockout mice.

Mice

Ranbp2-Flox

Strain Name：C57BL/6Smoc-Ranbp2tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200030

These mice carry loxP sites flanking exon 3 of Ranbp2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ranbp2 gene.

Mice

Ninj1-KO

Strain Name：C57BL/6Smoc-Ninj1em2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200615

Exon 2 of Ninj1 gene was deleted to generate Ninj1 knockout mice.

Mice

Sec31a-KO

Strain Name：C57BL/6Smoc-Sec31aem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200470

Exon 3 of Sec31a gene was deleted to generate Sec31a knockout mice.

Mice

Ctnnb1-Flox

Strain Name：C57BL/6Smoc-Ctnnb1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200154

These mice carry loxP sites flanking exon 2-6 of Ctnnb1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ctnnb1 gene.

Mice

Dicer1-Flox

Strain Name：C57BL/6Smoc-Dicer1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200158

These mice carry loxP sites flanking exon 23 of Dicer1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dicer1 gene.

Mice

Trp53-KO

Strain Name：B6.129-Trp53tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00011

A neo cassette replaces exons 2-11,including the start codon,of Trp53 (transformation related protein 53).Null homozygotes show high, early-onset tumor incidence;some have persistent hyaloid vasculature and cataracts.

Mice

NMG

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-001
Validation Data：Presence  |  Publications：59piece

Prkdc and Il2rg genes were both knocked-out in NOD mice. Lacking mature T, B and NK cells; Low immune rejection against human cells and tissues; Good tumorigenicity so that a small number of cells can form tumors; Significant improvement in the survival of transplanted human cells and tissues; Suitable for the transplantation of human hematopoietic stem cells and the preparation of humanized mouse models; Suitable as the carrier mice for the transplantation of heterologous cells and tissues.

Mice

Atp4b-IRES-CreERT2(2)

Strain Name：C57BL/6Smoc-Atp4bem2(IRES-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210119
Validation Data：Presence

An IRES-CreERT2 expression cassette was knocked into the Atp4b gene stop codon site. Besides,An IRES-CreERT2-WPRE-pA expression cassette were knock into the Atp4b gene start codon site to generate Atp4b-IRES-CreERT2(Stock No. NM-KI-210118) mice. ATP4B could serve as a tumor suppressor in the tumorigenesis and progression. This strain is useful in studying the function of gastric parietal cells in gastric epithelial homeostasis. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cre-expressing cells after tamoxifen treatment.

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