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Models

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Mice

Gpr141b-IRES-Cre

Strain Name:C57BL/6Smoc-Gpr141bem1(IRES-iCre)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200215

A IRES-iCre expression cassette was knocked into the Gpr141b gene start codon site.

Mice

Id2-CreERT2

Strain Name:C57BL/6Smoc-Id2em1(CreERT2-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200155

A CreERT2-WPRE-polyA expression cassette was knocked into the Id2 gene start codon site.

Mice

Mycn-TRE-EGFP

Strain Name:B6;129S-Mycntm1(TRE-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00008

A TRE site and a loxp EGFP casette were inserted into introns 1-2 to create a Dox-inducible N-myc gene silence mice.

Mice

Pbsn-2A-CreERT2

Strain Name:C57BL/6Smoc-Pbsnem1(V5-2A-CreERT2-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200190

A V5-2A-CreERT2-WPRE-polyA expression cassette was knocked into the Pbsn gene stop codon site.

Mice

Oprk1-2A-Cre

Strain Name:C57BL/6Smoc-Oprk1em1(2A-Cre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200299

2A-Cre expression cassette was knocked into the Oprk1 gene stop codon site. Oprk1 (opioid receptor, kappa 1) encodes opioid receptor which was expressed in multiple brain regions. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids.

Mice

Acan-IRES-CreERT2

Strain Name:C57BL/6Smoc-Acanem1(IRES-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200143

A IRES-CreERT2 expression cassette was knocked into the Acan gene stop codon site via CRISPR/Cas9 mediated recombination.

Mice

Bdnf-2A-CreERT2

Strain Name:C57BL/6Smoc-Bdnfem(2A-CreERT2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-220657

2A-CreERT2 expression cassette was knocked into the Bdnf gene stop codon site.

Mice

R26-CAG-LSL-hBCR/ABL

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-loxp-STOP-loxp-BCR-ABL-IRES-Luciferase-2A-tdTomato-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190127

These mice harbor a CAG-LSL-BCR-ABL-IRES-Luciferase-2A-tdTomato-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.

Mice

Ntrk2-CreERT2

Strain Name:C57BL/6Smoc-Ntrk2em1(CreERT2-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200146

A CreERT2-WPRE-polyA expression cassette was knocked into the Ntrk2 gene start codon site. Ntrk2 encodes the tropomyosin receptor kinase B (TrkB), transmission through which neurotrophic factors modify differentiation, plasticity, and synaptic transmission. When these Ntrk2-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Ntrk2 expressing cells.

Mice

R26-CAG-Cas9

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-Cas9)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-00120

These mice were established by crossing R26-(CAG-LSL-Cas9) and EIIA mice together.

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