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Models

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Mice

hICOS(BALB/c)

Strain Name：BALB/cAnSmoc-Icostm1(hICOS)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000046

The endogenous mouse Icos gene was replaced by human ICOS gene.

Mice

hIL3/hCSF2/hCSF1

Strain Name：C57BL/6Smoc-Il3tm1(hIL3)Csf2tm1(CSF2)Csf1tm2(CSF1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200271

hIL3(NM-HU-190009),hCSF1(NM-HU-190043),hCSF2(NM-HU-190046) were crossed together to generate hIL3/hCSF2/hCSF1 mice

Mice

H11-CAG-LSL-LSL-hMYCN-IRES-EGFP

Strain Name：C57BL/6Smoc-Igs2tm1(CAG-loxp-Neo-Stop-loxp-lox2272-Neo-Stop-lox2272-HA tag-NMYC-IRES-EFGP-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210145

A CAG-loxp-Neo-Stop-loxp-lox2272-Neo-Stop-lox2272-HA tag-NMYC-IRES-EFGP-WPRE-polyA expression cassette was knocked into via the lgs2 (H11) locus.

Mice

hTNFR2(BALB/c)

Strain Name：BALB/cAnSmoc-Tnfrsf1btm(hTNFRSF1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220499
Validation Data：Presence

The endogenous mouse Tnfrsf1b gene was replaced by human TNFRSF1B gene.

Mice

hIL3-hCSF2-Tg(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Tg(hIL3-hCSF2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215006
Validation Data：Presence

These transgenic mice carry humanized IL3 and humanized CSF2.

Mice

hIL3(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Il3tm4(hIL3)/Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-007

The hIL7(NM-HU-190009) mice were backcrossed to NMG genetic background, to create the new strain of hIL7(NMG) (NNMG-007) mice.

Mice

hCD19(BALB/c)

Strain Name：BALB/cAnSmoc-Cd19tm1(hCD19)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220606
Validation Data：Presence

The endogenous mouse Cd19 gene was replaced by human CD19 gene.

Mice

hCCL2

Strain Name：C57BL/6Smoc-Ccl2tm(hCCL2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220412

The endogenous mouse Ccl2 gene was replaced by human CCL2 gene.

Mice

hCCN2

Strain Name：C57BL/6Smoc-Ccn2tm(hCCN2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220517
Validation Data：Presence

The endogenous mouse Ccn2 gene was replaced by human CCN2 gene.

Mice

hBACE1

Strain Name：C57BL/6Smoc-Bace1tm(hBACE1)Smoc
Strain State：Developing | Cat. NO.：NM-HU-220263

The endogenous mouse Bace1 gene was replaced by human BACE1 gene.

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