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Models

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Mice

hMIEN1

Strain Name:C57BL/6Smoc-Mien1tm1(hMIEN1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200246

The endogenous mice Mien1 gene was replaced by human MIEN1 gene.

Mice

hIL3/hCSF2/hSIRPA(2)/hCD47

Strain Name:C57BL/6Smoc-Il3tm1(hIL3)Csf2tm1(CSF2)Sirpatm2(hSIRPA)Cd47tm1(hCD47)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200270

hIL3(NM-HU-190009),hSIRPA(NM-HU-18015),hCSF2(NM-HU-190046),CD47-HU(NM-HU-00050)was crossed together to generate hIL3/hCSF2/hSIRPA(2)/hCD47 mice.

Mice

hIL2RA/hCCR8

Strain Name:C57BL/6Smoc-Il2ratm1(hIL2RA)Ccr8tm1(hCCR8)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220096

hIL2RA(NM-HU-190064) mice were crossed with hCCR8(NM-HU-190053) mice to generate hIL2RA/hCCR8 mice.

Mice

Hlf-CreERT2

Strain Name:C57BL/6Smoc-Hlfem1(CreERT2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-230441
Validation Data:Presence

CreERT2 expression cassette was knocked into the Hlf gene .

Mice

hPD-1/hCD27(2)

Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd27tm2(hCD27)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000096

hPD-1(NM-HU-00015) was crossed with hCD27(2)(NM-HU-190035) to generate hPD-1/hCD27(2).

Mice

hNRP1

Strain Name:C57BL/6Smoc-Nrp1tm1(hNRP1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225046
Validation Data:Presence

The endogenous mouse Nrp1 gene was replaced by human NRP1 gene.

Mice

hCSF1(NMG)

Strain Name:NOD.Cg-PrkdcscidIl2rgem1Csf1tm2(hCSF1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220311

The endogenous mouse Csf1 gene was replaced by human CSF1 gene.

Mice

hCD3EDG/hB7H3

Strain Name:C57BL/6Smoc-Cd3etm(hCD3E)Cd3dtm(hCD3D)Cd3gtm(hCD3G)Cd276tm(hCD276)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220250

hB7H3 (NM-HU-00107)was crossed with hCD3EDG (NM-HU-220120) to generate hPD-1/hTIGIT.

Mice

H11-CAG-LSL-hACHE

Strain Name:C57BL/6Smoc-Igs2tm1(CAG-LSL-ACHE-WPRE-pA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00067

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven ACHE gene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. ACHE is expressed when bred to mice that express Cre recombinase.

Mice

hKLKB1

Strain Name:C57BL/6Smoc-Klkb1tm1(hKLKB1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225076
Validation Data:Presence

The endogenous mouse Klkb1 gene was replaced by human KLKB1 gene.

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