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Models

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Mice

H11-pAlb-NTCP-C9-IRES-EGFP

Strain Name：C57BL/6Smoc-Igs2em1(2xins-Alb-NTCP-C9 tag-IRES-EGFP-Wpre-pA-2xIns)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200054
Validation Data：Presence

These mice harbor a 2xins-Alb-NTCP-C9 tag-IRES-EGFP-Wpre-pA-2xIns cassette in the lgs2 locus generated by homologous recombination.

Mice

hCD3EDG/hCD47

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd47tm1(hCD47)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220127

hCD3EDG(NM-HU-220120) mice were crossed with hCD47(NM-HU-00050) mice to generate hCD3EDG/hCD47 mice.

Mice

hPD-1/hPD-L1/hCTLA-4

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPD-1)Cd274tm1(hPD-L1)Ctla4tm1(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200266

hCTLA4（NM-HU-00014）,hPD-1（NM-HU-00015）,hPD-L1（NM-HU-00062）were crossed together to generate hPD-1/hPD-L1/hCTLA4 mice

Mice

hNKG2A/hCD94

Strain Name：C57BL/6Smoc-Nkg2tm1(hNKG2A)Cd94tm1(hCD94)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000016

The endogenous mouse Nkg2 and Cd94 gene was replaced by human NKG2A and CD94 gene.

Mice

hHLA-E

Strain Name：C57BL/6Smoc-Igs2tm1(hHLA-E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200221

The endogenous human HLA-E gene (about 11kb) was knocked into the H11 locus via CRISPR/Cas9 mediated recombination.

Mice

hIL4/hIL4R(BALB/c)

Strain Name：BALB/cAnSmoc-Il4tm3(hIL4)Il4ratm1(hIL4RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220167
Validation Data：Presence

The endogenous mouse Il4,Il4ra gene was replaced by human IL4 gene.

Mice

hAPP

Strain Name：C57BL/6Smoc-Apptm(hAPP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220224

The endogenous mouse APP gene was replaced by human APP gene.

Mice

Hmga1-KO

Strain Name：C57BL/6Smoc-Hmga1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2114155

Exon 3-5 of Hmga1 gene was deleted to generate Hmga1 knockout mice.

Mice

hIL2/hIL2RA

Strain Name：C57BL/6Smoc-Il2tm3(hIL2)Il2ratm1(hIL2RA)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200275
Validation Data：Presence

hIL2(NM-HU-190048) was crossed with hIL2R(NM-HU-190064) to generate IhIL2/hIL2RA mice.

Mice

hLILRB2-hLILRB3-Tg

Strain Name：C57BL/6Smoc-Tg(loxp-LILRB2-LILRB3-FRT-PGK-PuropolyA-FRT-lox2272)
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-220136
Validation Data：Presence

These transgenic mice harbor loxp-hLILRB2-hLILRB3-FRT-PGK-PuropolyA-FRT-lox2272 expression cassettes.

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