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Models

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Mice

hIL4

Strain Name：C57BL/6Smoc-Il4tm3(hIL4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190071
Validation Data：Presence

The endogenous mouse Il4 gene was completely or partially replaced by human IL4 gene via ESC targeting.

Mice

hPD-1/hCTLA-4(BALB/c)

Strain Name：BALB/cAnSmoc-Pdcd1tm1(hPDCD1)Ctla4tm1(hCTLA4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200277
Validation Data：Presence

hPD-1(NM-HU-190079) was crossed with hCTLA4(2)(NM-HU-190078)to generate hPD-1/hCTLA4 mice

Mice

hIL2/hIL2RB/hIL2RG

Strain Name：C57BL/6Smoc-Il2rgtm1(IL2RG)Il2tm3(hIL2)Il2rbtm1(hIL2RB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220145

hIL2RG(NM-HU-200007) and IL2RB(NM-HU-2000055) mice were crossed with hIL2(NM-HU-190048) mice to generate hIL2/hIL2RB/hIL2RG mice.

Mice

hADAM17

Strain Name：C57BL/6Smoc-Adam17tm(hADAM17)Smoc
Strain State：Developing | Cat. NO.：NM-HU-220260

The endogenous mouse Adam17 gene was replaced by human ADAM17 gene.

Mice

hLAIR1

Strain Name：C57BL/6Smoc-Lair1tm2(LAIR1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000011

The endogenous mouse Lair1 gene was replaced by human LAIR1 gene .

Mice

hLGALS9

Strain Name：C57BL/6Smoc-Lgals9tm(hLGALS9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215009
Validation Data：Presence

The endogenous mice Lgals9 gene was replaced by human LGALS9 gene.

Mice

hCXCL16

Strain Name：C57BL/6Smoc-Cxcl16tm(hCXCL16)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215000
Validation Data：Presence

The endogenous mice Cxcl16 gene was replaced by human CXCL16 gene.

Mice

Hcn4-DreERT2

Strain Name：C57BL/6Smoc-Hcn4em1(kozak-DreER-WPRE-A)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200199
Publications：1piece

A kozak-DreER-WPRE-pA expression cassette was knocked into the Hcn4 gene start codon site.

Mice

hIL2RA/hIL2RG

Strain Name：C57BL/6Smoc-Il2rgtm1(IL2RG)Il2ratm1(hIL2RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220144

hIL2RG(NM-HU-200007) mice were crossed with hIL2RA(NM-HU-190064) mice to generate hIL2RA/hIL2RG mice.

Mice

hPD-L1/hSIRPA(2)

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd274tm1(hCD274)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000099

hPD-L1(NM-HU-00062) was crossed with hSIRPA(2)(NM-HU-18015) to generate hPD-L1/hSIRPA(2).

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