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Models

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Mice

hTIGIT/hPVR

Strain Name：C57BL/6Smoc-Tigittm1(hTIGIT)Pvrtm1(hPVR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000091
Validation Data：Presence

These mice are obtained through breeding of hTIGIT(NM-HU-00053) and hPVR(NM-HU-190012) mice.

Mice

hIL2RB/hPD-1

Strain Name：C57BL/6Smoc-Il2rbtm1(hIL2RB)Pdcd1tm1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220036

hIL2RB(NM-HU-2000055) mice were crossed with hPD-1(NM-HU-00015) to generate hIL2RB/hPD-1 mice.

Mice

hSIRPA(2)/hCD47/hPD-1/hPD-L1(2)

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Pdcd1tm1(hPDCD1)Cd274tm2(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220029

hSIRPA(2)(NM-HU-18015), hCD47(NM-HU-00050) and hPD-1(NM-HU-00015) was crossed with hPD-L1(2)(NM-HU-190039）to generate hSIRPA(2)/hCD47/hPD-1/hPD-L1(2) mice.

Mice

Hexb-Linker-2A-CreERT2

Strain Name：C57BL/6Smoc-Hexbem1(Linker-3xFLAG-P2A-CreERT2-FRT-WPRE-pA-FRT)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215050

Linker-3xFLAG-P2A-CreERT2-FRT-WPRE-pA-FRT expression cassette was knocked into the Hexb gene.

Mice

hSPN

Strain Name：C57BL/6Smoc-Spntm1(hSPN)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225032
Validation Data：Presence

The endogenous mouse Spn gene was replaced by human SPN gene.

Mice

hGDF15/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Gdf15tm1(hGDF15)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220151

hGDF15(NM-HU-215002) and hPD-1(NM-HU-00015)mice were crossed with hPD-L1(NM-HU-00062) mice to generate hIL2/hIL2RB/hIL2RG mice.

Mice

hOX40/hOX40L(2)

Strain Name：C57BL/6Smoc-Tnfrsf4tm1(hTNFRSF4)Tnfsf4tm2(hTNFSF4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200263
Validation Data：Presence

hOX40L(2)(NM-HU-200005)was crossed with hOX40(NM-HU-00041)to generate hOX40/hOX40L(2)mice

Mice

H11-pAlb-hBAFF

Strain Name：C57BL/6Smoc-Igs2tm1(pAlb-hBAFF-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-232137
Validation Data：Presence

The pAlb-hBAFF-pA expression cassette was knocked into the H11 locus.

Mice

hPD-1/hPD-L1/hTIGIT

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Tigittm1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200267

hTIGIT（NM-HU-00053）,hPD-1（NM-HU-00015）,hPD-L1（NM-HU-00062）were crossed together to generate hPD-1/hPD-L1/hTIGIT mice

Mice

hSIRPA(2)/hCD47/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210358

hSIRPA(2)(NM-HU-18015)，hCD47（NM-HU-00050), hPD-1（NM-HU-00015）, hPD-L1（NM-HU-00062）was crossed together to generate hSIRPA(2)/hCD47/hPD-1/hPD-L1 mice.

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