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Models

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Mice

hIL5/hIL5R(2)

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Il5ratm2(hIL5RA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220010
Validation Data：Presence

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(3)(Stock No.NM-HU-220011) function similarly to hIL5/hIL5R(2) mice, for more detailed information please contact our technical advisor.

Mice

hGEM

Strain Name：C57BL/6Smoc-Gemtm1(hGem)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200249

The endogenous mice Gem gene was replaced by human GEM gene.

Mice

hIL2-Tg(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Tg(hIL2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-NSG-010
Validation Data：Presence

These transgenic mice carry humanized IL2.

Mice

hIL2

Strain Name：C57BL/6Smoc-Il2tm3(hIL2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190048
Validation Data：Presence

The endogenous mouse Il2 gene was replaced by human IL2 gene.

Mice

hPD-1/hPD-L1/hCD47/hSIRPA(BALB/c)

Strain Name：BALB/cAnSmoc-Pdcd1tm(hPDCD1)Cd274tm(hPD-L1)Sirpatm4(hSIRPA)Cd47tm1(hCD47)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220143

hSIRPA/hCD47(BALB/c)(NM-HU-210020) mice was crossed with hPD-1/ hPD-L1(BALB/c)(NM-HU-220142) mice to generate hPD-1/hPD-L1/hCD47/hSIRPA(BALB/c) mice.

Mice

hIL5/hIL5R(3)

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Il5ratm3(hIL5RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220011
Validation Data：Presence

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(2)(Stock No.NM-HU-220010) function similarly to hIL5/hIL5R(3) mice, for more detailed information please contact our technical advisor.

Mice

H11-CAG-RSR-tdTomato

Strain Name：C57BL/6Smoc-Igs2em1(CAG-RSR-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18009
Publications：3piece

These mice harbor a CAG-Rox-STOP-Rox-tdTomato conditional expression cassette in mouse H11 locus via homologous recombination.

Mice

hSIRPA(2)/hCD47/hCTLA-4

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Ctla4tm1(hCTLA4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210368

hCTLA4(NM-HU-00014) was crossed with hSIRPA(2)/hCD47(NM-HU-2000111）to generate hSIRPA(2)/hCD47/hCTLA4 mice

Mice

hPD-1/hTIGIT/hTIM3

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Tigittm1(hTIGIT) Havcr2tm1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190029

hPD-1(NM-HU-00015),hTIGIT(NM-HU-00053) were crossed with hTIM3(NM-HU-00054) to generate hPD-1/hTIGIT/hTIM3.

Mice

hIL2/hIL2RA(BALB/c)

Strain Name：BALB/cAnSmoc-Il2tm3(hIL2)Il2ratm1(hIL2RA)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220018
Validation Data：Presence

The endogenous mouse Il2 and Il2ra gene was replaced respectively by human IL2 and IL2RA gene.

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