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Models

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Mice

hIL1RAP

Strain Name：C57BL/6Smoc-Il1raptm3(hIL1RAP)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000070
Validation Data：Presence

The endogenous mouse Il1rap gene was replaced by human IL1RAP gene.

Mice

hPD-L1(2)/hCCR8

Strain Name：C57BL/6Smoc-Cd274tm2(hPD-L1)Ccr8tm1(hCCR8)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210401

hPD-1(2)(NM-HU-190039) was crossed with hCCR8(NM-HU-190053) to generate hPD-L1(2)/hCCR8 mice.

Mice

hPD-1/hCD40

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd40tm1(hCD40)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190017

hPD-1(NM-HU-00015) was crossed with hCD40(NM-HU-00076) to generate hPD-1/hCD40.

Mice

hOX40/hCTLA-4

Strain Name：C57BL/6Smoc-Tnfrsf4tm3(hTNFRSF4)Ctla4tm1(hCTLA4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00105

These mice are OX40 and CTLA4 double knockin mouse models which can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hIL13(BALB/c)

Strain Name：BALB/cAnSmoc-Il13tm2(hIL13)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220019
Validation Data：Presence

The endogenous mouse Il13 gene was replaced by human IL13 gene.

Mice

hMARCO

Strain Name：C57BL/6Smoc-Marcotm1(hMARCO)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000029
Validation Data：Presence

The endogenous mouse Marco gene was replaced by human MARCO gene.

Mice

hLYPD3

Strain Name：C57BL/6Smoc-Lypd3tm1(hLYPD3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200248

The endogenous mice Lypd3 gene was replaced by human LYPD3 gene.

Mice

hPD-1/hCD3E

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd3etm1(hCD3E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18021

hPD-1（NM-HU-00015）was crossed with hCD3E（NM-HU-00114）to generate hPD-1/hCD3E。

Mice

hTHPO

Strain Name：C57BL/6Smoc-Thpotm1(hTHPO)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000062

The endogenous mouse Thpo gene was replaced by human THPO gene.

Mice

hPD-1/hIL1B

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Il1btm3(hIL1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210018

hPD-1(NM-HU-00015) was crossed with hIL1B(NM-HU-190047) to generate hPD-1/hIL1B mice

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