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Models

About 5,119 results
Mice

hF12

Strain Name:C57BL/6Smoc-F12tm1(hF12)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210017
Validation Data:Presence

The endogenous mice F12 gene was replaced by human F12 gene.

Mice

hIL1A

Strain Name:C57BL/6Smoc-Il1atm1(hIL1A)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-215071
Validation Data:Presence

The endogenous mouse Il1a gene was replaced by human IL1A gene.

Mice

hICOS

Strain Name:C57BL/6Smoc-Icostm1(hICOS)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00052
Validation Data:Presence

The endogenous mouse Icos gene was replaced by human ICOS gene. While hICOS(2)(Stock No.NM-HU-190030) mice function similarly to hICOS mice,for more detailed information please contact our technical advisor.

Mice

hPD-L1/hSIGLEC15

Strain Name:C57BL/6Smoc-Cd274tm1(hCD274)Siglec15tm1(hSIGLEC15)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000103

hPD-L1(NM-HU-00062) was crossed with hSIGLEC15(NM-HU-190037) to generate hPD-L1/hSIGLEC15.

Mice

hSIRPA(2)/hCD47

Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000111
Validation Data:Presence

This SIRPA and CD47 double Knock-in strain is established by crossing hSIRPA and hCD47 mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.While hSIRPA/hCD47 (Stock No.NM-HU-190019) have been pulled from shelves for some reasons.

Mice

hSERPINC1

Strain Name:C57BL/6Smoc-Serpinc1tm1(hSERPINC1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225075
Validation Data:Presence

The endogenous mouse Serpinc1 gene was replaced by human SERPINC1 gene.

Mice

hSIGLEC10

Strain Name:C57BL/6Smoc-Siglecgtm1(hSIGLEC10)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000061
Validation Data:Presence

The endogenous mouse Siglecg gene was replaced by human SIGLEC10 gene.

Mice

hPD-1/hTLR9

Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1)Tlr9 tm1(hTLR9)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190023

hPD-1(NM-HU-00015) was crossed with hTLR9(NM-HU-18016) to generate hPD-1/hTLR9.

Mice

hPD-1/hSEMA4D

Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1)Sema4dtm1(hSemA4D)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190033

hPD-1(NM-HU-00015) was crossed with hSEMA4D(NM-HU-00117) to generate hPD-1/hSEMA4D.

Mice

hIL11

Strain Name:C57BL/6Smoc-Il11tm1(hIL11)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-204981

The endogenous mice Il11 gene was replaced by human IL11 gene.

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