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Models

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Mice

hMELTF

Strain Name：C57BL/6Smoc-Meltftm(hMELTF)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215011
Validation Data：Presence

The endogenous mouse Meltf gene was replaced by human MELTF gene.

Mice

hPSGL-1(2)

Strain Name：C57BL/6Smoc-Selplgtm2(hSELPLG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210026
Validation Data：Presence

The endogenous mice Selplg gene was completely or partially replaced by human SELPLG gene via CRISPR/Cas9 mediated recombination.

Mice

hPD-1/hSTING

Strain Name：C57BL/6Smoc-Tmem173tm1(hTMem173)Pdcd1tm1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000104

hPD-1(NM-HU-00015) was crossed with hSTING(NM-HU-190036) to generate hPD-1/hSTING.

Mice

hPD-L1/hCTLA-4

Strain Name：C57BL/6Smoc-Ctla4tm1(hCTLA4)Cd274tm1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00102
Validation Data：Presence

hPD-L1(NM-HU-00062) was crossed with hCTLA4(NM-HU-00014)to generate hPD-1/hCTLA4 mice

Mice

hDDR1

Strain Name：C57BL/6Smoc-Ddr1tm3(hDDR1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225086
Validation Data：Presence

The endogenous mouse Ddr1 gene was replaced by human DDR1 gene.

Mice

hPVRL2

Strain Name：C57BL/6Smoc-Nectin2tm1(hNECTIN2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000084
Validation Data：Presence

The endogenous mouse Nectin2 gene was replaced by human PVRL2 gene.

Mice

hAPOE3

Strain Name：C57BL/6Smoc-Apoetm3(hAPOE3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190003
Validation Data：Presence

This APOE3 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE3 corresponding sequence by homologous recombination.

Mice

hITGB1

Strain Name：C57BL/6Smoc-Itgb1tm1(hITGB1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225040
Validation Data：Presence

The endogenous mouse Itgb1 gene was replaced by human ITGB1 gene.

Mice

hDMPK

Strain Name：C57BL/6Smoc-Dmpktm1(hDMPK)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225084
Validation Data：Presence

The endogenous mouse Dmpk gene was replaced by human DMPK gene.

Mice

hIGFBP2

Strain Name：C57BL/6Smoc-Igfbp2tm1(hIGFBP2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225085

The endogenous mouse Igfbp2 gene was replaced by human IGFBP2 gene.

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