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Models

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Mice

hAPOE4

Strain Name：C57BL/6Smoc-Apoetm2(hAPOE4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190002
Validation Data：Presence

This APOE4 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE4 corresponding sequence by homologous recombination.

Mice

hPD-1(BALB/c)

Strain Name：BALB/cAnSmoc-Pdcd1tm1(hPDCD1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190079
Validation Data：Presence

The endogenous mouse Pdcd1 gene was replaced by human PDCD1(PD-1) gene .

Mice

hCD93

Strain Name：C57BL/6Smoc-Cd93tm1(hCD93)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215065
Validation Data：Presence

The endogenous mouse Cd93 gene was replaced by human CD93 gene.

Mice

hCXCL13

Strain Name：C57BL/6Smoc-Cxcl13tm1(hCXCL13)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225079
Validation Data：Presence

The endogenous mouse Cxcl13 gene was replaced by human CXCL13 gene.

Mice

hIL6ST

Strain Name：C57BL/6Smoc-Il6sttm1(hIL6ST)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204980

The endogenous mice Il6st gene was replaced by human IL6ST gene.

Mice

hIGHG4

Strain Name：C57BL/6Smoc-Ighg1tm1(hIGHG4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225092
Validation Data：Presence

The endogenous mouse Ighg1 gene was replaced by human IGHG4 gene.

Mice

hFCGR2B/h4-1BB(2)

Strain Name：C57BL/6Smoc-Fcgr2btm2(FCGR2B)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210352
Validation Data：Presence

hFCGR2B(NM-HU-2000010) was crossed with h4-1BB (NM-HU-190077) to generate hFCGR2B/h4-1BB mice.

Mice

hIFNGR1/hIFNGR2

Strain Name：C57BL/6Smoc-Ifngr1tm3(hIFNGR1)Ifngr2tm(hIFNGR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220003
Validation Data：Presence

hIFNGR1(NM-HU-190076) was crossed with hIFNGR2(NM-HU-215010) to generate hIFNGR1/hIFNGR2 mice.

Mice

hPD-1/hTIM3

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Havcr2tm1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00103
Validation Data：Presence

hPD-1(NM-HU-00015) was crossed with hTIM3(NM-HU-00054)to generate hPD-1/hTIM3 mice

Mice

hCTLA-4/hCCR8(BALB/c)

Strain Name：BALB/cAnSmoc-Ccr8tm1(hCCR8)Ctla4tm1(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220050

hCTLA4(BALB/c)(NM-HU-190078) was crossed with hCCR8(BALB/c)(NM-HU-2000048) to generate hCTLA4/hCCR8(BALB/c) mice．

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