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Models

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Mice

R26-CAG-LNL-ddCas9

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LNL-ddCas9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00063

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven ddCas9. The targeted mutation was inserted into the Gt(ROSA)26Sor locus.

Mice

Abcd3-Flox

Strain Name：C57BL/6Smoc-Abcd3em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-251666

These mice carry loxP sites flanking exon 2 of Abcd3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Abcd3 gene.

Mice

Abcc6-KO

Strain Name：C57BL/6Smoc-Abcc6em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200005

Exon 5-6 of Abcc6 gene was deleted to generate Abcc6 knockout mice.

Mice

R26-CAG-Cas9

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-Cas9)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00120
Validation Data：Presence

These mice were established by crossing R26-(CAG-LSL-Cas9) and EIIA mice together.

Mice

Aars1-Flox

Strain Name：C57BL/6Smoc-Aarsem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-226339

These mice carry loxP sites flanking exon 3-4 of Aars gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aars gene.

Mice

Pah-KO

Strain Name：C57BL/6Smoc-Pahem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-2110565
Validation Data：Presence

Exon 2-5 of pah gene was deleted to generate pah knockout mice. The homozygous (HO) mice have a certain mortality rate (approximately 15%). Heterozygous (HE) mice are recommended for colony establishment. If you need to purchase homozygous (HO) mice directly for experiments, it is recommended to purchase an additional 15%-20% to avoid mouse death affecting subsequent experiments.

Mice

Lrrc10-KO

Strain Name：C57BL/6Smoc-Lrrc10em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201002

Exon 1 of Lrrc10 gene was deleted to generate Lrrc10 knockout mice.

Mice

hIL3/hCSF2/hCSF1

Strain Name：C57BL/6Smoc-Il3tm1(hIL3)Csf2tm1(CSF2)Csf1tm2(CSF1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200271

hIL3(NM-HU-190009),hCSF1(NM-HU-190043),hCSF2(NM-HU-190046) were crossed together to generate hIL3/hCSF2/hCSF1 mice

Mice

Aagab-Flox

Strain Name：C57BL/6Smoc-Aagabem1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Aagab gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aagab gene.

Mice

Aa543186-KO

Strain Name：C57BL/6Smoc-Aa543186em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 1-2 of Aa543186 gene was deleted to generate Aa543186 knockout mice.

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