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Models

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Mice

Tie1-2A-Cre

Strain Name：C57BL/6Smoc-Tie1em1(2A-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18023

A 2A-Cre coexpression cassette is inserted befor the stop codon of mouse Tie1 gene via homologous recombination to establish a tamoxifen inducible Tie1-Cre tool stain. This strain can be used to knockout target gene in Tie1+ cells when crossed with mice which carry loxp sites flanking target gene.

Mice

Aadacl4fm4-Flox

Strain Name：C57BL/6Smoc-Aadacl4fm4em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253858

These mice carry loxP sites flanking exon 2 of Aadacl4fm4 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadacl4fm4 gene.

Mice

Csf2rb2-2A-Cre

Strain Name：C57BL/6Smoc-Csf2rb2em1(2A-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210001
Validation Data：Presence

2A-Cre expression cassette was knocked into the Csf2rb2 gene. Csf2rb2 is also known as colony stimulating factor 2 receptor. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. The gene product has been involved in the modulation of memory.

Mice

hNR1I3

Strain Name：C57BL/6Smoc-Nr1i3tm2(hNR1I3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200253
Validation Data：Presence

The endogenous mice Nr1i3 gene was replaced by human NR1I3 gene.

Mice

Amhr2-IRES-CreERT2

Strain Name：C57BL/6Smoc-Amhr2em(IRES-2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-204995

IRES-2A-CreERT2 expression cassette was knocked into the Amhr2 gene via CRISPR/Cas9 mediated recombination.

Mice

Sirt3-KO

Strain Name：C57BL/6Smoc-Sirt3em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190368

This Sirt3 knockout mouse model was generated by knocking out the exon 2-3 region of the Sirt3.

Mice

Chga-CreERT2

Strain Name：C57BL/6Smoc-Chgaem(CreERT2-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-204993
Validation Data：Presence

CreERT2-Wpre-pA expression cassette was knocked into the Chga gene.

Mice

Mesp1-CreERT2

Strain Name：C57BL/6Smoc-Mesp1em(CreERT2-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215087

CreERT2-Wpre-pA expression cassette was knocked into the Mesp1 gene .

Mice

hCD3EDG/hCD40

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd40tm1(hCD40)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220116

hCD3EDG(NM-HU-220120) mice were crossed with hCD40(NM-HU-00076) to generate hCD3EDG//hCD40 mice.

Mice

Meox1-Dre

Strain Name：C57BL/6Smoc-Meox1em1(Dre-Wpre-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200174

A Dre-Wpre-polyA expression cassette was knocked into the Meox1 gene start codon site.

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