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Mice

Pax7-IRES-Cre

Strain Name:C57BL/6Smoc-Pax7em1(IRES-iCre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200120

A IRES-iCre expression cassette was knocked into the Pax7 gene stop codon site. Pax7 is expressed in myogenic progenitor cells. Pax7 is essential for the myogenic potential, survival, and proliferation of myogenic progenitors. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Pax7.

Mice

Myf5-Cre

Strain Name:C57BL/6Smoc-Myf5em1(Cre-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200147

A Cre-WPRE-polyA expression cassette was knocked into the Myf5 gene start codon site. Myogenic factor 5 (Myf5) belongs to the MRF family transcription factors that regulate myogenesis. It is expressed in the skeletal muscle and satellite cells. Severe loss of skeletal muscle following ablation of Myf5-expressing progenitors. This strain is useful in studying the differentiation of skeletal muscle.

Mice

Ikzf3-KO

Strain Name:C57BL/6Smoc-Ikzf3em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-2104251

Exon 8 of Ikzf3 gene was deleted to generate Ikzf3 knockout mice.

Mice

hIL3/hCSF2

Strain Name:C57BL/6Smoc-Il3tm3(hIL3)Csf2tm3(hCSF2)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190065

The endogenous mouse Il3 and Csf2 gene was replaced by human IL3 and CSF2 gene.

Mice

Foxp3-DreERT2

Strain Name:C57BL/6Smoc-Foxp3em5(IRES-DreER)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200198

A IRES-DreER expression cassette was knocked into the Foxp3 gene stop codon site.

Mice

Ptf1a-CreERT2

Strain Name:C57BL/6Smoc-Ptf1aem1(CreERT2-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200118

A CreERT2-WPRE-pA expression cassette was knocked into the Ptf1a gene start codon site.

Mice

hIL1RL2

Strain Name:C57BL/6Smoc-Il1rl2em1(hIL1RL2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-215057

The endogenous mouse Il1rl2 gene was replaced by human IL1RL2 gene.

Mice

hNR1I2

Strain Name:C57BL/6Smoc-Nr1i2em3(hNR1I2)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000066

The endogenous mouse Nr1i2 gene was replaced by human NR1I2 gene.

Mice

hMARCO

Strain Name:C57BL/6Smoc-Marcoem1(hMARCO)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000029

The endogenous mouse Marco gene was replaced by human MARCO gene.

Mice

Atp4b-IRES-CreERT2(2)

Strain Name:C57BL/6Smoc-Atp4bem2(IRES-CreERT2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-210119

An IRES-CreERT2 expression cassette was knocked into the Atp4b gene stop codon site. Besides,An IRES-CreERT2-WPRE-pA expression cassette were knock into the Atp4b gene start codon site to generate Atp4b-IRES-CreERT2(Stock No. NM-KI-210118) mice. ATP4B could serve as a tumor suppressor in the tumorigenesis and progression. This strain is useful in studying the function of gastric parietal cells in gastric epithelial homeostasis. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cre-expressing cells after tamoxifen treatment.

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