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Models

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Mice

Il17a-Cre

Strain Name：C57BL/6Smoc-Il17aem1(iCre-polyA(SV40))Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200137

A iCre-polyA expression cassette was knocked into the Il17a gene start codon site. This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying autoimmune inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis.

Mice

hNECTIN4

Strain Name：C57BL/6Smoc-Nectin4tm1(hNECTIN4)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210016

The endogenous mice Nectin4 gene was replaced by human NECTIN4 gene.

Mice

Krt14-2A-DreERT2

Strain Name：C57BL/6Smoc-Krt14em3(2A-DreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190125

A 2A-DreERT2 expression cassette was knocked into the Krt14 gene stop codon site.

Mice

hCD3EDG/hEpCAM

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Epcamtm1(hEPCAM) /Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220123

hCD3EDG(NM-HU-220120) mice were crossed with hEpCAM(NM-HU-210032) mice to generate hCD3EDG/hEpCAM mice.

Mice

hPD-1/hVEGFR2

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Kdrtm2(hKDR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000098

hPD-1(NM-HU-00015) was crossed with hKDR(NM-HU-00098) to generate hPD-1/hKDR.

Mice

Fcgr2b-Fcgr3-Fcgr4-KO/hCTLA-4

Strain Name：C57BL/6Smoc-Fcgr2bem1Fcgr3em1Fcgr4em1Ctla4em1(hCTLA4)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-220069

The Fcgr2b-Fcgr3-Fcgr4-KO/hCTLA4 mouse model was obtained by deleting all sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hCTLA4(NM-HU-00014) mouse.

Mice

R26-Renilla-Luc

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-Renilla-Luc)-NSmoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00091

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Renilla-Luc gene. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination.

Mice

Atp4b-2A-CreERT2

Strain Name：C57BL/6Smoc-Atp4bem1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200240

A 2A-CreERT2-WPRE-pA expression cassette was knocked into the Atp4b gene stop codon site.

Mice

Mc4r-2A-Cre

Strain Name：C57BL/6Smoc-Mc4rem1(T2A-Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200220

A T2A-Cre expression cassette was knocked into the Mc4r gene stop codon site.

Mice

Apoa2-KO

Strain Name：C57BL/6Smoc-Apoa2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200035

Exon 3 of Apoa2 gene was deleted to generate Apoa2 knockout mice.

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