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Models

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Mice

Abcb8-Flox

Strain Name：C57BL/6Smoc-Abcb8em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Abcb8 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Abcb8 gene.

Mice

hMIF

Strain Name：C57BL/6Smoc-Mifem3(hMIF)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000030

The endogenous mouse Mif gene was replaced by human MIF gene.

Mice

hF11

Strain Name：C57BL/6Smoc-F11em1(hF11)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210015

The endogenous mice F11 gene was replaced by human F11 gene

Mice

hIL13/hOX40

Strain Name：C57BL/6Smoc-Il13em2(hIL13)Tnfrsf4em1(hTNFRSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220024

hIL13(NM-HU-190069) was crossed with hOX40(NM-HU-00041) to generate hIL13/hOX40 mice.

Mice

hSIRPA(2)/hCD47/hCTLA-4

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Ctla4em1(hCTLA4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210368

hCTLA4(NM-HU-00014) was crossed with hSIRPA(2)/hCD47(NM-HU-2000111）to generate hSIRPA(2)/hCD47/hCTLA4 mice

Mice

Il33-KO(2)

Strain Name：C57BL/6Smoc-Il33em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190436

Il33-KO(2) mice(Stock No.NM-KO-190436) carry a knockout allele derived from the targeted deletion of exon 3-7. While Il33-KO mice(Stock No.NM-KO-00099) have been pulled from shelves for some reasons and Il33-KO(3) mice(Stock No.NM-KO-210206) carrying the exon 2 deletion.

Mice

Abcc8-KO(2)

Strain Name：C57BL/6Smoc-Abcc8em2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-225150

exon 8-16 of Abcc8 gene was deleted to generate Abcc8 knockout mice.

Mice

A4galt-KO

Strain Name：C57BL/6Smoc-A4galtem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200001

Exon 3 of A4galt gene was deleted to generate A4galt knockout mice.

Mice

hIL1A

Strain Name：C57BL/6Smoc-Il1atm1(hIL1A)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215071

The endogenous mouse Il1a gene was replaced by human IL1A gene.

Mice

hOX40/hCTLA-4

Strain Name：C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4)Ctla4em1(hCTLA4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00105

These mice are OX40 and CTLA4 double knockin mouse models which can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

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