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Models

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Mice

hIFNGR2

Strain Name：C57BL/6Smoc-Ifngr2tm(hIFNGR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215010
Validation Data：Presence

The endogenous mouse Ifngr2 gene was replaced by human IFNGR2 gene.

Mice

Ctsk-2A-CreERT2

Strain Name：C57BL/6Smoc-Ctskem1(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200067
Publications：1piece

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ctsk gene stop codon site.

Mice

hPD-L1/hVISTA

Strain Name：C57BL/6Smoc-Visrtm1(hVSIR)Cd274tm1(hCD274)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000094

hPD-L1(NM-HU-00062) was crossed with hVISTA(NM-HU-00118) to generate hPD-L1/hVISTA.

Mice

hFAS

Strain Name：C57BL/6Smoc-Fastm1(hTNFRSF6)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-210007
Validation Data：Presence

The endogenous mice Fas gene was replaced by human FAS gene.

Mice

hICOS/hICOSL

Strain Name：C57BL/6Smoc-Icosltm1(hICOSLG) Icostm1(hICOS)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18018
Validation Data：Presence

This ICOS and ICOSL double knockin strain is established by crossing ICOS-HU and ICOSL-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hCD3E/hPD-L1

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd274tm1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210449
Validation Data：Presence

hCD3E(NM-HU-00114) was crossed with hPD-L1(NM-HU-00062) to generate hCD3E/hPD-L1 mice

Mice

hHER3(2)

Strain Name：C57BL/6Smoc-Erbb3tm2(hERBB3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225068
Validation Data：Presence

The endogenous mouse Erbb3 gene was replaced by human ERBB3 gene.

Mice

hIL21R

Strain Name：C57BL/6Smoc-Il21rtm1(hIL21R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210031
Validation Data：Presence

The endogenous mice Il21r gene was completely or partially replaced by human IL21R gene via ESC targeting.

Mice

Col2a1-2A-CreERT2

Strain Name：C57BL/6Smoc-Col2a1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18029
Validation Data：Presence  |  Publications：1piece

A 2A-CreERT2 expression cassette was knocked into the stop codon of Col2a1 gene to establish a Col2a1-CreERT2 recombinase tool mouse.The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

Mice

hRSPO1

Strain Name：C57BL/6Smoc-Rspo1tm1(hRSPO1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225041
Validation Data：Presence

The endogenous mouse Rspo1 gene was replaced by human RSPO1 gene.

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