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Models

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Mice

hIL1RAP

Strain Name：C57BL/6Smoc-Il1raptm3(hIL1RAP)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-2000070

The endogenous mouse Il1rap gene was replaced by human IL1RAP gene.

Mice

Fah-KO

Strain Name：C57BL/6Smoc-Fahem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-191202

Partial exon 8 of Fah gene was deleted to generate Fah knockout mice.

Mice

hPD-1/hPD-L1/hLAG3

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Lag3em1(hLAG3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190028

hPD-1(NM-HU-00015),hPD-L1(NM-HU-00062) were crossed with hLAG3(NM-HU-00049) to generate hPD-1/hPD-L1/hLAG3.

Mice

hDMPK

Strain Name：C57BL/6Smoc-Dmpktm1(hDMPK)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225084

The endogenous mouse Dmpk gene was replaced by human DMPK gene.

Mice

hIL15RA

Strain Name：C57BL/6Smoc-Il15ratm1(hIL15RA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215070

The endogenous mouse Il15ra gene was replaced by human IL15RA gene.

Mice

hPD-1/hCD40

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd40em1(hCD40)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190017

hPD-1(NM-HU-00015) was crossed with hCD40(NM-HU-00076) to generate hPD-1/hCD40.

Mice

H11-CAG-ddCre

Strain Name：C57BL/6Smoc-Igs2em1(CAG-ddCre-V5-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00086

These H11-(CAG-ddCre-V5-polyA) mice are established by knocking CAG-LSL-ddCre-V5-polyA conditional expression cassette in mouse H11 loci.

Mice

hKLRK1

Strain Name：C57BL/6Smoc-Klrk1em1(hKLRK1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190005

The endogenous mouse Klrk1 gene was replaced by human KLRK1 gene.

Mice

Pax8-Cre

Strain Name：C57BL/6Smoc-Pax8em1(Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200151

A Cre-WPRE-polyA expression cassette was knocked into the Pax8 gene start codon site.

Mice

R26-LNL-PB

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LNL-PB-V5)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00065

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven piggyBac transposase. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination. PiggyBac transposase is expressed when bred to mice that express Cre recombinase.

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