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Mice

Mc4r-KO

Strain Name：C57BL/6Smoc-Mc4rem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200357
Validation Data：Presence

Exon 1 of Mc4r gene was deleted to generate Mc4r knockout mice.

Mice

hTNFR2/hFCGR2B

Strain Name：C57BL/6Smoc-Tnfrsf1btm2(hTNFRSF1B)Fcgr2btm3(FCGR2B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210404

hTNFRSF1B (NM-HU-190010) was crossed with hFCGR2B (NM-HU-2000010) to generate hTNFRSF1B/hFCGR2B mice.

Mice

Vip-IRES-Cre

Strain Name：C57BL/6Smoc-Vipem1(IRES-iCre-SV40-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200100
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Vip gene stop codon site. Vip encodes vasoactive intestinal polypeptide. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in cells expressing. This strain is useful for studying bronchiectasis, immunomodulatory and anti-inflammatory.

Mice

Pax7-IRES-CreERT2

Strain Name：C57BL/6Smoc-Pax7em1(IRES-Cre-ERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200099
Validation Data：Presence

A IRES-Cre-ERT2 expression cassette was knocked into the Pax7 gene stop codon site. Pax7 is expressed in myogenic progenitor cells. Pax7 is essential for the myogenic potential, survival, and proliferation of myogenic progenitors. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Pax7 after tamoxifen treatment.

Mice

hCD3E/hLAG3

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Lag3tm1(hLAG3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220027

hCD3E(NM-HU-00114) was crossed with hLAG3( NM-HU-00049) to generate hCD3E/hLAG3 mice.

Mice

hCD248

Strain Name：C57BL/6Smoc-Cd248tm1(hCD248)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-225028

The endogenous mouse Cd248 gene was replaced by human CD248 gene.

Mice

hPD-1/hOX40

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Tnfrsf4tm3(hTNFRSF4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00108

hPD-1（NM-HU-00015）was crossed with hOX40（NM-HU-00041）to generate hPD-1/hOX40.

Mice

Hopx-2A-DreERT2

Strain Name：C57BL/6Smoc-Hopxem1(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190035
Validation Data：Presence  |  Publications：1piece

A 2A-DreERT2 expression cassette was knocked into the Hopx gene stop codon site.

Mice

Akt2-KO

Strain Name：C57BL/6Smoc-Akt2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190742

Exon 3-4 of Akt2 gene was deleted to generate Akt2 knockout mice.

Mice

Vil1-CreERT2

Strain Name：C57BL/6Smoc-Vil1em(CreERT2)2Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225020
Validation Data：Presence

CreERT2 expression cassette was knocked into the Vil1 gene .

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