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Models

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Mice

hTLR9

Strain Name：C57BL/6Smoc-Tlr9tm1(hTLR9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18016
Validation Data：Presence

This TLR9 humanized mouse model was established by replacing the mouse Tlr9 gene exon2 with the human TLR9 corresponding sequence by homologous recombination.

Mice

hB7H4(2)

Strain Name：C57BL/6Smoc-Vtcn1tm2(hVTCN1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190075

Extracellular domain of mouse Vtcn1 gene was replaced by human VTCN1 gene. While hB7H4(Stock No.NM-HU-190004) mice function similarly to hB7H4(2) mice,for more detailed information please contact our technical advisor.

Mice

Drd2-KO

Strain Name：C57BL/6Smoc-Drd2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190265

This Drd2 knockout mouse model was generated by knocking out the exon 3 region of the Drd2.

Mice

hAPOE2

Strain Name：C57BL/6Smoc-Apoetm4(hAPOE2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190013
Validation Data：Presence

This APOE2 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE2 corresponding sequence by homologous recombination.

Mice

Alpl-KO

Strain Name：C57BL/6Smoc-Alpltm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18058
Validation Data：Presence

This Alpl knockout mouse model was obtained by knocking out the exon 3-4 region of the Alpl gene.

Mice

Cd200-KO

Strain Name：C57BL/6Smoc-Cd200em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190029

This Cd200 knockout mouse model was generated by knocking out the exon 2 region of the Cd200 .

Mice

hPD-L1(E3-4)

Strain Name：C57BL/6Smoc-Cd274tm2(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190039
Validation Data：Presence

Extracellular domain of mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene. While hPD-L1(Stock No.NM-HU-00062) mice function similarly to hPD-L1(2) mice,for more detailed information please contact our technical advisor.

Mice

Snca-KO

Strain Name：C57BL/6Smoc-Sncaem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190380

This Snca knockout mouse model was generated by knocking out the exon4 region of the Snca.

Mice

hIl5

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190001
Validation Data：Presence

This IL5 humanized mouse model was established by replacing the mouse Il5 gene coding exons and introns with the human TLR9 corresponding sequence by homologous recombination.

Mice

hAPOE4

Strain Name：C57BL/6Smoc-Apoetm2(hAPOE4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190002
Validation Data：Presence

This APOE4 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE4 corresponding sequence by homologous recombination.

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