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Study of Gene Functions

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Dysgenesis model

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Prss37 gene knockout infertility mouse model. SMOC has developed the Prss37 gene knockout mouse model (Prss37 KO, Model No.: NM -KO-00016) by ES cell targeting. It is a homozygous male infertility model.

IBD model

EAE animal model

Psoriasis Mouse Model

P53 CKO Mouse Model

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Our own-developed mouse model of p53 conditional knockout (p53-CKO) can be mated with mice carrying tissue-specific Cre expression to obtain mice with homozygous deletion of p53 in specific tissues or cells. These mice can be used for tumorigenesis and tumor mechanistic studies.

Pten CKO Mouse Model

Our own-developed mouse model of Pten conditional knockout (Pten-CKO) can be mated with mice carrying tissue-specific Cre expression to obtain mice with homozygous deletion of Pten in specific tissues or cells, thus avoiding the embryonic death caused by systemic and homozygous Pten knockout. Pten-CKO mice can be used to study tumorigenesis, anti-tumor targets, neurogenesis, glial differentiation and cerebellar development.

How to Verify Your Cre-lox Model

Gene-editing proposal

model mouse

Using SMOC’s gene targeting artificial intelligent expert system-Smarteddi, you can input the name of the gene you want to knockout and the cloud-based search engine will show you the solution.

Nervous System

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The model of nerve injury induced by surgery or drugs can be used to study the mechanism of nerve injury and to evaluate drug efficacy.