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Mice

hSIRPA(2)/hCD47/hPD-L1

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd274em1(hCD274)Cd47em1(hCD47)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000095

hPD-L1(NM-HU-00062),hCD47(NM-HU-00050) was crossed with hSIRPA(2) (NM-HU-18015) to generate hSIRPA(2)/hCD47/hPD-L1.

Mice

hPD-1/hICOS(2)

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Icosem1(hICOS)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000100

hPD-1(NM-HU-00015) was crossed with hICOS(2)(NM-HU-190030) to generate hPD-1/hICOS(2).

Mice

Sox2-CreERT2

Strain Name：C57BL/6Smoc-Sox2em1(CreERT2-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200084

The coding region of Sox2 gene was replaced by a CreERT2-polyA expression cassette.

Mice

Opn4-Cre

Strain Name：C57BL/6Smoc-Opn4em1(Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200304

Cre-WPRE-polyA expression cassette was knocked into the Opn4 gene start codon site. The melanopsin gene (Opn4) encodes a functional photopigment. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying circadian rhythm regulation.

Mice

Lepr-RSR-CreERT2

Strain Name：C57BL/6Smoc-Leprtm1(rox-stop-rox-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210112

rox-stop-rox-CreERT2-WPRE-polyA expression cassette was knocked into the Lepr gene.

Mice

R26-CAG-LSL-hEGFR*T790M/del19-Luc-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-EGFR T790M-del19-luciferase-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190009

A SA-2xpolyA-CAG-LSL-EGFR(T790M-del19)-IRES-luciferase-2A-tdTomato-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the EGFR(T790M-del19) protein.

Mice

Pdyn-IRES-Cre

Strain Name：C57BL/6Smoc-Pdynem1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200089

A IRES-iCre expression cassette was knocked into the Pdyn gene stop codon site. Pdyn encodes prodynorphin. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying depression, stress, anxiety, pain response, circadian rhythm and appetite control.

Mice

Slc32a1-IRES-Cre

Strain Name：C57BL/6Smoc-Slc32a1em1(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200081

A IRES-iCre expression cassette was knocked into the Slc32a1 gene stop codon site.

Mice

Egr2-Cre

Strain Name：C57BL/6Smoc-Egr2em1(iCre-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200132

A iCre-Wpre-pA expression cassette was knocked into the Egr2 gene start codon site.

Mice

R26-CAG-LSL-Trem2

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-Loxp-Stop-Loxp-Trem2-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215105

CAG-Loxp-Stop-Loxp-Trem2-Wpre-pA expression cassette was knocked into the the Rosa26 locus.

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