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Models

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Mice

Dux-KO

Strain Name：C57BL/6Smoc-Duxem1Smoc
Strain State：Developing | Cat. NO.：NM-KO-242098

The Gm19459 gene, Gm4981 gene, Duxf3 gene, Gm10807 gene and AW822073 gene were deleted to generate Dux gene cluster knockout mouse.

Mice

H11-CAG-LSL-Myc

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00039

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

Mice

Pten-KO

Strain Name：C57BL/6Smoc-Ptenem3Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18002

Exon5 of Pten gene was deleted to generate Pten knockout mice.

Mice

hCLEC4C

Strain Name：C57BL/6Smoc-Dppa3tm1(hCLEC4C)Smoc
Strain State：Developing | Cat. NO.：NM-HU-225073

The human CLEC4C gene was knocked in the close location of the Dppa3 gene.

Mice

Abcb11-KO

Strain Name：C57BL/6Smoc-Abcb11em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18010

Exon5 of Abcb11 gene was deleted to generate Abcb11 knockout mice.

Mice

Ahr-KO

Strain Name：C57BL/6Smoc-Ahrem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18008

Exon3 of Ahr gene was deleted to generate Ahr knockout mice. The homozygous female mice of this strain had impaired fertility. There have been reports of deaths caused by genetic modification. For details, click on the MGI ID in the genetic information.

Mice

Sh3rf2-KO

Strain Name：C57BL/6Smoc-Sh3rf2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190449

exon5 of Sh3rf2 gene was deleted to generate Sh3rf2 knockout mice.

Mice

Prrx1-KO

Strain Name：C57BL/6Smoc-Prrx1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00165

Exon1 of Prrx1 gene was targeted to generate Prrx1 knockout mice.

Mice

Il17a-KO

Strain Name：C57BL/6Smoc-IL17aem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00131

Exon1 of IL17a gene was deleted to generate IL17a knockout mice.

Mice

Atg5-KO

Strain Name：C57BL/6Smoc-Atg5em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18004

Exon3 of Atg5 gene was targeted and a additional 58bp sequence insertion caused a frameshift mutation.

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