Standard GEMMs
|
|
Strain Name：C57BL/6JSmo-Cdkn2a/Cdkn2bem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-235093
|
|
|
|
||
|
|
||
|
|
Strain Name：C57BL/6Smoc-Cdkn2aipnlem1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD
|
|
|
|
||
|
|
Strain Name：C57BL/6JSmo-Cdkn2bem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-2115067
|
|
|
|
Strain Name：C57BL/6JSmo-Cdkn2Bem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190621
Research Application：This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression.
|
|
|
|
Strain Name：C57BL/6JSmo-Cdkn2cem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-205110
Disease Connection：medulloblastoma
|
|
|
|
Strain Name：C57BL/6JSmo-Cdkn2Cem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-2114003
Disease Connection：medulloblastoma
|
|
|
|
