hMSTN

Nomenclature

C57BL/6Smoc-Mstntm(hMSTN)Smoc

Cat. NO.

NM-HU-230106

Strain State

Repository Live

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Gene Summary

Gene Symbol
Mstn

Model Description

The endogenous mouse Mstn gene was replaced by human MSTN gene.

Validation Data

image.png

Fig.1 Detection of MSTN expression in mammary gland by RT-PCR. 

Wild type: only one band at 135 bp with primers F1/R1(mMstn);

Homozygous: only one band at 291 bp with primers F2/R2(hMSTN).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hMSTN(A) and mMSTN(B) expression in serum by ELISA (female, 7-8wks, n=3). 

Abbr.  HO, homozygous; WT, wild type.

Note. The Human MSTN ELISA Kit cross-reacted with mouse MSTN and humanized MSTN.


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