hRHO

Nomenclature

C57BL/6Smoc-Rhotm1(hRHO)Smoc

Cat. NO.

NM-HU-234891

Strain State

Repository Live

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Gene Summary

Gene Symbol
Rho

Synonyms

Ops; RP4; Opn2; Noerg1

NCBI ID

212541

MGI ID

97914

Ensembl ID

ENSMUSG00000030324

Pubmed

Rho

Human Ortholog

RHO

Model Description

The endogenous mouse Rho gene was replaced by human RHO gene.

Validation Data

image.png

Fig.1 Detection of RHO expression in testis by RT-PCR. 

Wild type: only one band at 460 bp with primers F1/R1(mRho);

Homozygous: only one band at 116 bp with primers F2/R2(hRHO).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human RHO expression in HO hRHO knockin mice by IF. 

Eyes were collected from homozygous hRHO mice, and analyzed by IF with anti-human RHO antibody.

Note. The anti-human RHO Antibody cross-reacted with mouse and humanized RHO. 

Abbr. HO/HO, homozygous; WT, wild type.

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